Package: sRACIPE 1.99.1
sRACIPE: Systems biology tool to simulate gene regulatory circuits
sRACIPE implements a randomization-based method for gene circuit modeling. It allows us to study the effect of both the gene expression noise and the parametric variation on any gene regulatory circuit (GRC) using only its topology, and simulates an ensemble of models with random kinetic parameters at multiple noise levels. Statistical analysis of the generated gene expressions reveals the basin of attraction and stability of various phenotypic states and their changes associated with intrinsic and extrinsic noises. sRACIPE provides a holistic picture to evaluate the effects of both the stochastic nature of cellular processes and the parametric variation.
Authors:
sRACIPE_1.99.1.tar.gz
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sRACIPE.pdf |sRACIPE.html✨
sRACIPE/json (API)
NEWS
# Install 'sRACIPE' in R: |
install.packages('sRACIPE', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org')) |
Bug tracker:https://github.com/lusystemsbio/sracipe/issues
Pkgdown site:https://vivekkohar.github.io
- CoupledToggleSwitchSA - Five coupled toggle switches
- EMT1 - A circuit for epithelial to mesenchymal transition
- EMT2 - A circuit for epithelial to mesenchymal transition including microRNAs
- allTypesDemoCircuit - A circuit with every interaction type for simulations
- cellCycle - A circuit for modeling the yeast cell cycle
- configData - Configuration Data
- demoCircuit - A toggle switch circuit for demonstrations
- repressilator - A loop motif for demonstrating limit cycles in gene expression
On BioConductor:sRACIPE-1.99.1(bioc 3.21)sRACIPE-1.22.0(bioc 3.20)
researchfieldsystemsbiologymathematicalbiologygeneexpressiongeneregulationgenetargetcpp
Last updated 30 days agofrom:bce5d5dcfc. Checks:1 OK, 11 NOTE. Indexed: yes.
Target | Result | Latest binary |
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Doc / Vignettes | OK | Mar 27 2025 |
R-4.5-win-x86_64 | NOTE | Mar 27 2025 |
R-4.5-mac-x86_64 | NOTE | Mar 27 2025 |
R-4.5-mac-aarch64 | NOTE | Mar 27 2025 |
R-4.5-linux-x86_64 | NOTE | Mar 27 2025 |
R-4.4-win-x86_64 | NOTE | Mar 27 2025 |
R-4.4-mac-x86_64 | NOTE | Mar 27 2025 |
R-4.4-mac-aarch64 | NOTE | Mar 27 2025 |
R-4.4-linux-x86_64 | NOTE | Mar 27 2025 |
R-4.3-win-x86_64 | NOTE | Mar 27 2025 |
R-4.3-mac-x86_64 | NOTE | Mar 27 2025 |
R-4.3-mac-aarch64 | NOTE | Mar 27 2025 |
Exports:.RacipeSEannotationannotation<-densityPlotRacipeSEsracipeCircuitsracipeCircuit<-sracipeCombineRacipeSEsracipeConfigsracipeConfig<-sracipeConvergesracipeConvergeDistsracipeGenParamNamessracipeGetTSsracipeHeatmapSimilaritysracipeICsracipeIC<-sracipeKnockDownsracipeNormalizesracipeOverExpsracipeParamssracipeParams<-sracipePlotCircuitsracipePlotDatasracipePlotParamBifursracipeSimulatesracipeUniqueStates
Dependencies:abindaskpassbase64encBiobaseBiocGenericsbitopsbslibcachemcaToolsclicodetoolscolorspacecrayoncurlDelayedArraydigestdoFuturedoRNGevaluatefansifarverfastmapfontawesomeforeachfsfuturefuture.applygenericsGenomeInfoDbGenomeInfoDbDataGenomicRangesggplot2globalsgluegplotsgridExtragtablegtoolsherehighrhtmltoolshtmlwidgetshttrIRangesisobanditeratorsjquerylibjsonliteKernSmoothknitrlabelinglatticelifecyclelistenvmagrittrMASSMatrixMatrixGenericsmatrixStatsmemoisemgcvmimemunsellnlmeopensslparallellypillarpkgconfigplyrpngR6rappdirsRColorBrewerRcppRcppEigenRcppTOMLreshape2reticulaterlangrmarkdownrngtoolsrprojrootRSpectraS4ArraysS4VectorssassscalesSparseArraystringistringrSummarizedExperimentsystibbletinytexUCSC.utilsumaputf8vctrsviridisLitevisNetworkwithrxfunXVectoryaml