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# CITATION file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "sRACIPE" in publications use:'
type: software
license: MIT
title: 'sRACIPE: Systems biology tool to simulate gene regulatory circuits'
version: 1.21.0
identifiers:
- type: doi
  value: 10.32614/CRAN.package.sRACIPE
- type: url
  value: https://geneex.jax.org/
abstract: sRACIPE implements a randomization-based method for gene circuit modeling.
  It allows us to study the effect of both the gene expression noise and the parametric
  variation on any gene regulatory circuit (GRC) using only its topology, and simulates
  an ensemble of models with random kinetic parameters at multiple noise levels. Statistical
  analysis of the generated gene expressions reveals the basin of attraction and stability
  of various phenotypic states and their changes associated with intrinsic and extrinsic
  noises. sRACIPE provides a holistic picture to evaluate the effects of both the
  stochastic nature of cellular processes and the parametric variation.
authors:
- family-names: Kohar
  given-names: Vivek
  email: vivek.kohar@gmail.com
  orcid: https://orcid.org/0000-0003-1813-1597
- family-names: Lu
  given-names: Mingyang
preferred-citation:
  type: article
  title: Role of noise and parametric variation in the dynamics of gene regulatory
    circuits
  authors:
  - family-names: Kohar
    given-names: Vivek
    email: vivek.kohar@gmail.com
    orcid: https://orcid.org/0000-0003-1813-1597
  - family-names: Lu
    given-names: Mingyang
  journal: npj Systems Biology and Applications
  year: '2018'
  volume: '4'
  url: https://www.nature.com/articles/s41540-018-0076-x
  start: '40'
repository: https://bioc.r-universe.dev
repository-code: https://github.com/vivekkohar/sRACIPE
commit: 7c85e5b8a6947d972006864d26413dd4a3cc191b
url: https://vivekkohar.github.io/sRACIPE/
contact:
- family-names: Kohar
  given-names: Vivek
  email: vivek.kohar@gmail.com
  orcid: https://orcid.org/0000-0003-1813-1597