Package: timescape 1.29.0

Maia Smith

timescape: Patient Clonal Timescapes

TimeScape is an automated tool for navigating temporal clonal evolution data. The key attributes of this implementation involve the enumeration of clones, their evolutionary relationships and their shifting dynamics over time. TimeScape requires two inputs: (i) the clonal phylogeny and (ii) the clonal prevalences. Optionally, TimeScape accepts a data table of targeted mutations observed in each clone and their allele prevalences over time. The output is the TimeScape plot showing clonal prevalence vertically, time horizontally, and the plot height optionally encoding tumour volume during tumour-shrinking events. At each sampling time point (denoted by a faint white line), the height of each clone accurately reflects its proportionate prevalence. These prevalences form the anchors for bezier curves that visually represent the dynamic transitions between time points.

Authors:Maia Smith [aut, cre]

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timescape.pdf |timescape.html
timescape/json (API)

# Install 'timescape' in R:
install.packages('timescape', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

On BioConductor:timescape-1.29.0(bioc 3.20)timescape-1.28.0(bioc 3.19)

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

bioconductor-package

14 exports 0.82 score 41 dependencies 1 mentions

Last updated 2 months agofrom:b335594f86

Exports:checkAlphacheckClonalPrevcheckCloneColourscheckGtypePositioningcheckMinDimscheckPertscheckRequiredInputscheckTreeEdgesgetMutationsDataprocessUserDatarenderTimescapereplaceSpacestimescapetimescapeOutput

Dependencies:base64encbslibcachemclidigestdplyrevaluatefansifastmapfontawesomefsgenericsgluegtoolshighrhtmltoolshtmlwidgetsjquerylibjsonliteknitrlifecyclemagrittrmemoisemimepillarpkgconfigR6rappdirsrlangrmarkdownsassstringistringrtibbletidyselecttinytexutf8vctrswithrxfunyaml

TimeScape vignette

Rendered fromtimescape_vignette.Rmdusingknitr::rmarkdownon Jun 30 2024.

Last update: 2018-08-30
Started: 2017-02-11

Readme and manuals

Help Manual

Help pageTopics
TimeScapetimescape
Widget output function for use in ShinycheckAlpha checkClonalPrev checkCloneColours checkGtypePositioning checkMinDims checkPerts checkRequiredInputs checkTreeEdges getMutationsData processUserData renderTimescape replaceSpaces timescapeOutput