Package: timescape
Title: Patient Clonal Timescapes
Version: 1.37.0
Authors@R: person("Maia", "Smith", email = "maiaannesmith@gmail.com", role = c("aut", "cre"))
Description: TimeScape is an automated tool for navigating temporal
        clonal evolution data. The key attributes of this
        implementation involve the enumeration of clones, their
        evolutionary relationships and their shifting dynamics over
        time. TimeScape requires two inputs: (i) the clonal phylogeny
        and (ii) the clonal prevalences. Optionally, TimeScape accepts
        a data table of targeted mutations observed in each clone and
        their allele prevalences over time. The output is the TimeScape
        plot showing clonal prevalence vertically, time horizontally,
        and the plot height optionally encoding tumour volume during
        tumour-shrinking events. At each sampling time point (denoted
        by a faint white line), the height of each clone accurately
        reflects its proportionate prevalence. These prevalences form
        the anchors for bezier curves that visually represent the
        dynamic transitions between time points.
Depends: R (>= 3.3)
Imports: htmlwidgets (>= 0.5), jsonlite (>= 0.9.19), stringr (>=
        1.0.0), dplyr (>= 0.4.3), gtools (>= 3.5.0)
biocViews: Visualization, BiomedicalInformatics
License: GPL-3
RoxygenNote: 6.0.1
Suggests: knitr, rmarkdown
VignetteBuilder: knitr
Config/pak/sysreqs: cmake make libicu-dev libuv1-dev
Repository: https://bioc.r-universe.dev
Date/Publication: 2026-04-28 12:45:09 UTC
RemoteUrl: https://github.com/bioc/timescape
RemoteRef: HEAD
RemoteSha: b0f7631ab5919eaec4e5b4f48d0217d916f8abc9
NeedsCompilation: no
Packaged: 2026-07-07 06:04:30 UTC; root
Author: Maia Smith [aut, cre]
Maintainer: Maia Smith <maiaannesmith@gmail.com>