Package: synergyfinder 3.13.0
Shuyu Zheng
synergyfinder: Calculate and Visualize Synergy Scores for Drug Combinations
Efficient implementations for analyzing pre-clinical multiple drug combination datasets. It provides efficient implementations for 1.the popular synergy scoring models, including HSA, Loewe, Bliss, and ZIP to quantify the degree of drug combination synergy; 2. higher order drug combination data analysis and synergy landscape visualization for unlimited number of drugs in a combination; 3. statistical analysis of drug combination synergy and sensitivity with confidence intervals and p-values; 4. synergy barometer for harmonizing multiple synergy scoring methods to provide a consensus metric of synergy; 5. evaluation of synergy and sensitivity simultaneously to provide an unbiased interpretation of the clinical potential of the drug combinations. Based on this package, we also provide a web application (http://www.synergyfinder.org) for users who prefer graphical user interface.
Authors:
synergyfinder_3.13.0.tar.gz
synergyfinder_3.13.0.zip(r-4.5)synergyfinder_3.13.0.zip(r-4.4)synergyfinder_3.13.0.zip(r-4.3)
synergyfinder_3.13.0.tgz(r-4.4-any)synergyfinder_3.13.0.tgz(r-4.3-any)
synergyfinder_3.13.0.tar.gz(r-4.5-noble)synergyfinder_3.13.0.tar.gz(r-4.4-noble)
synergyfinder_3.13.0.tgz(r-4.4-emscripten)synergyfinder_3.13.0.tgz(r-4.3-emscripten)
synergyfinder.pdf |synergyfinder.html✨
synergyfinder/json (API)
NEWS
| # Install 'synergyfinder' in R: |
| install.packages('synergyfinder', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org')) |
- NCATS_screening_data - A high-throughput 3 drug combination screening data
- ONEIL_screening_data - A high-throughput 2 drugs combination screening data with replication
- mathews_screening_data - A high-throughput drug combination screening data
On BioConductor:synergyfinder-3.13.0(bioc 3.20)synergyfinder-3.12.0(bioc 3.19)
This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.
Last updated 2 months agofrom:98b379022a
Exports:.AdjustColumnName.ExtractMultiDrugPlotDataBlissCalculateCSSCalculateIC50CalculateRICalculateSensitivityCalculateSynergyCorrectBaseLineDimensionReductionExtractSingleDrugFindModelParFindModelTypeFitDoseResponseGenerateSurfaceHighlightBarPlotHSAImputeIC50LoewePlot2DrugContourPlot2DrugHeatmapPlot2DrugSurfacePlotBarometerPlotDoseResponsePlotDoseResponseCurvePlotMultiDrugBarPlotMultiDrugSurfacePlotSensitivitySynergyPlotSynergyPredictResponseReshapeDataZIP
Dependencies:abindaskpassbackportsbase64encbitbit64blobbootbroombslibcachemcallrcarcarDatacellrangercheckmateclassclassIntclicliprclustercodetoolscolorspaceconflictedcowplotcpp11crayoncrosstalkcurldata.tableDBIdbplyrDerivdigestdoBydotCall64dplyrdrcdtplyre1071evaluatefansifarverfastmapfieldsFNNfontawesomeforcatsforeachFormulaformula.toolsfsfurrrfuturegarglegenericsggforceggplot2ggrepelglmnetglobalsgluegoogledrivegooglesheets4gstatgtablegtoolshavenhighrhmshtmltoolshtmlwidgetshttridsintervalsisobanditeratorsjomojquerylibjsonliteKernSmoothknitrkriginglabelinglaterlatticelazyevallifecyclelistenvlme4lubridatemagrittrmapsMASSMatrixMatrixModelsmemoisemetRmgcvmicemicrobenchmarkmimeminqamitmlmodelrmultcompmunsellmvtnormnleqslvnlmenloptrnnetnumDerivopenssloperator.toolsordinalpanparallellypbapplypbkrtestpermutepillarpkgconfigplotlyplotrixplyrpolyclipprettyunitsprocessxprogresspromisesproxypspurrrquantregR6raggrappdirsRColorBrewerRcppRcppEigenreadrreadxlrematchrematch2reprexreshape2rlangrmarkdownrpartrstudioapirvests2sandwichsassscalesselectrsfsftimeshapespspacetimespamSparseMSpatialExtremesstarsstringistringrsurvivalsyssystemfontstextshapingTH.datatibbletidyrtidyselecttidyversetimechangetinytextweenrtzdbucminfunitsutf8uuidvctrsveganviridisLitevroomwithrwkxfunxml2xtsyamlzoo
