# -------------------------------------------- # CITATION file created with {cffr} R package # See also: https://docs.ropensci.org/cffr/ # -------------------------------------------- cff-version: 1.2.0 message: 'To cite package "synergyfinder" in publications use:' type: software license: MPL-2.0 title: 'synergyfinder: Calculate and Visualize Synergy Scores for Drug Combinations' version: 3.13.0 identifiers: - type: doi value: 10.32614/CRAN.package.synergyfinder abstract: Efficient implementations for analyzing pre-clinical multiple drug combination datasets. It provides efficient implementations for 1.the popular synergy scoring models, including HSA, Loewe, Bliss, and ZIP to quantify the degree of drug combination synergy; 2. higher order drug combination data analysis and synergy landscape visualization for unlimited number of drugs in a combination; 3. statistical analysis of drug combination synergy and sensitivity with confidence intervals and p-values; 4. synergy barometer for harmonizing multiple synergy scoring methods to provide a consensus metric of synergy; 5. evaluation of synergy and sensitivity simultaneously to provide an unbiased interpretation of the clinical potential of the drug combinations. Based on this package, we also provide a web application (http://www.synergyfinder.org) for users who prefer graphical user interface. authors: - family-names: Zheng given-names: Shuyu email: shuyu.zheng@helsinki.fi - family-names: Tang given-names: Jing email: jing.tang@helsinki.fi preferred-citation: type: article title: 'SynergyFinder Plus: Toward Better Interpretation and Annotation of Drug Combination Screening Datasets' authors: - family-names: Zheng given-names: Shuyu email: shuyu.zheng@helsinki.fi - family-names: Wang given-names: Wenyu - family-names: Aldahdooh given-names: Jehad - family-names: Malyutina given-names: Alina - family-names: Shadbahr given-names: Tolou - family-names: Tanoli given-names: Ziaurrehman - family-names: Pessia given-names: Alberto - family-names: Tang given-names: Jing email: jing.tang@helsinki.fi journal: Genomics, Proteomics & Bioinformatics year: '2022' url: https://doi.org/10.1016/j.gpb.2022.01.004 start: 20(3):587-596 repository: https://bioc.r-universe.dev commit: 98b379022a4abe1e395de9f6608914484d9cca33 url: http://www.synergyfinder.org date-released: '2024-01-22' contact: - family-names: Zheng given-names: Shuyu email: shuyu.zheng@helsinki.fi