singIST Vignette
Abstract of singIST as a Bioconductor library | Introduction | Inputs of singIST | Superpathways | Example 1: Superpathway with the same pathway gene set for each cell type | Example 2: Superpathway with different gene sets per cell type (optional) | Human scRNA-seq | Example 1: Dendritic Cells in regulating Th1/Th2 Development | Example 2: Cytokine-Cytokine receptor interaction superpathway | Disease model scRNA-seq | Example: Oxazolone mouse model of Atopic Dermatitis | Fit Optimal asmbPLS-DA and compute validation metrics for the optimal model | Example: fitting cytokine-cytokine receptor interaction and dendritic cells | in regulating | Compute recapitulation metrics | Example: Evaluating Oxazolone mouse model of Atopic Dermatitis for Dendritic | Cells and cytokine superpathways | Appendix: Missing value handling in human pseudobulk matrices | Problem setup | Step 1: Impute the training fold using multiblock MFA. | Step 2: Impute the validation fold by projection (no re-fitting). | Session Info