Package: epialleleR 1.15.1

Oleksii Nikolaienko

epialleleR: Fast, Epiallele-Aware Methylation Caller and Reporter

Epialleles are specific DNA methylation patterns that are mitotically and/or meiotically inherited. This package calls and reports cytosine methylation as well as frequencies of hypermethylated epialleles at the level of genomic regions or individual cytosines in next-generation sequencing data using binary alignment map (BAM) files as an input. Among other things, this package can also extract and visualise methylation patterns and assess allele specificity of methylation.

Authors:Oleksii Nikolaienko [aut, cre]

epialleleR_1.15.1.tar.gz
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epialleleR.pdf |epialleleR.html
epialleleR/json (API)
NEWS

# Install 'epialleleR' in R:
install.packages('epialleleR', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/bbcg/epialleler/issues

Uses libs:
  • curl– Easy-to-use client-side URL transfer library
  • bzip2– High-quality block-sorting file compressor library
  • xz-utils– XZ-format compression library
  • zlib– Compression library
  • c++– GNU Standard C++ Library v3

On BioConductor:epialleleR-1.15.1(bioc 3.21)epialleleR-1.14.0(bioc 3.20)

dnamethylationepigeneticsmethylseqlongreadbioconductordna-methylationepiallelenext-generation-sequencingsamtoolscurlbzip2xz-utilszlibcpp

5.98 score 4 stars 5 scripts 195 downloads 13 exports 21 dependencies

Last updated 3 months agofrom:c786e6eab6. Checks:1 OK, 10 NOTE. Indexed: yes.

TargetResultLatest binary
Doc / VignettesOKFeb 15 2025
R-4.5-win-x86_64NOTEFeb 15 2025
R-4.5-mac-x86_64NOTEFeb 15 2025
R-4.5-mac-aarch64NOTEFeb 15 2025
R-4.5-linux-x86_64NOTEFeb 15 2025
R-4.4-win-x86_64NOTEFeb 15 2025
R-4.4-mac-x86_64NOTEFeb 15 2025
R-4.4-mac-aarch64NOTEFeb 15 2025
R-4.3-win-x86_64NOTEFeb 15 2025
R-4.3-mac-x86_64NOTEFeb 15 2025
R-4.3-mac-aarch64NOTEFeb 15 2025

Exports:callMethylationextractPatternsgenerateAmpliconReportgenerateBedEcdfgenerateBedReportgenerateCaptureReportgenerateCytosineReportgenerateMhlReportgenerateVcfReportplotPatternspreprocessBampreprocessGenomesimulateBam

Dependencies:askpassBHBiocGenericscurldata.tablegenericsGenomeInfoDbGenomeInfoDbDataGenomicRangeshttrIRangesjsonlitemimeopensslR6RcppRhtslibS4VectorssysUCSC.utilsXVector

The epialleleR User's Guide

Rendered fromepialleleR.Rmdusingknitr::rmarkdownon Feb 15 2025.

Last update: 2024-11-16
Started: 2021-04-08

The epialleleR output values

Rendered fromvalues.Rmdusingknitr::rmarkdownon Feb 15 2025.

Last update: 2024-10-10
Started: 2023-09-29

Readme and manuals

Help Manual

Help pageTopics
callMethylationcallMethylation
extractPatternsextractPatterns
generateBedEcdfgenerateBedEcdf
generateBedReportgenerateAmpliconReport generateBedReport generateCaptureReport
generateCytosineReportgenerateCytosineReport
generateMhlReportgenerateMhlReport
generateVcfReportgenerateVcfReport
plotPatternsplotPatterns
preprocessBampreprocessBam
preprocessGenomepreprocessGenome
simulateBamsimulateBam