Package: awst 1.13.0

Davide Risso

awst: Asymmetric Within-Sample Transformation

We propose an Asymmetric Within-Sample Transformation (AWST) to regularize RNA-seq read counts and reduce the effect of noise on the classification of samples. AWST comprises two main steps: standardization and smoothing. These steps transform gene expression data to reduce the noise of the lowly expressed features, which suffer from background effects and low signal-to-noise ratio, and the influence of the highly expressed features, which may be the result of amplification bias and other experimental artifacts.

Authors:Davide Risso [aut, cre, cph], Stefano Pagnotta [aut, cph]

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awst.pdf |awst.html
awst/json (API)
NEWS

# Install 'awst' in R:
install.packages('awst', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Bug tracker:https://github.com/drisso/awst/issues

On BioConductor:awst-1.13.0(bioc 3.20)awst-1.12.0(bioc 3.19)

bioconductor-package

2 exports 0.61 score 28 dependencies

Last updated 2 months agofrom:398c0ee68d

Exports:awstgene_filter

Dependencies:abindaskpassBiobaseBiocGenericscrayoncurlDelayedArrayGenomeInfoDbGenomeInfoDbDataGenomicRangeshttrIRangesjsonlitelatticeMatrixMatrixGenericsmatrixStatsmimeopensslR6S4ArraysS4VectorsSparseArraySummarizedExperimentsysUCSC.utilsXVectorzlibbioc

Introduction to awst

Rendered fromawst_intro.Rmdusingknitr::rmarkdownon Jul 02 2024.

Last update: 2021-05-04
Started: 2021-04-14

Readme and manuals

Help Manual

Help pageTopics
Asymmetric Within-Sample Transformationawst awst,matrix-method awst,SummarizedExperiment-method
Gene filtering based on heterogeneitygene_filter gene_filter,matrix-method gene_filter,SummarizedExperiment-method