{ "_id": "6a4999224ae8ee07ee132930", "Package": "awst", "Title": "Asymmetric Within-Sample Transformation", "Version": "1.21.0", "Authors@R": "c(person(given = \"Davide\",\nfamily = \"Risso\",\nrole = c(\"aut\", \"cre\", \"cph\"),\nemail = \"risso.davide@gmail.com\",\ncomment = c(ORCID = \"0000-0001-8508-5012\")),\nperson(given = \"Stefano\",\nfamily = \"Pagnotta\",\nrole = c(\"aut\", \"cph\"),\nemail = \"smpagnotta@gmail.com\",\ncomment = c(ORCID = \"0000-0002-8298-9777\")))", "Description": "We propose an Asymmetric Within-Sample Transformation\n(AWST) to regularize RNA-seq read counts and reduce the effect\nof noise on the classification of samples. AWST comprises two\nmain steps: standardization and smoothing. These steps\ntransform gene expression data to reduce the noise of the lowly\nexpressed features, which suffer from background effects and\nlow signal-to-noise ratio, and the influence of the highly\nexpressed features, which may be the result of amplification\nbias and other experimental artifacts.", "License": "MIT + file LICENSE", "Encoding": "UTF-8", "RoxygenNote": "7.1.1", "URL": "https://github.com/drisso/awst", "BugReports": "https://github.com/drisso/awst/issues", "biocViews": "Normalization, GeneExpression, RNASeq, Software,\nTranscriptomics, Sequencing, SingleCell", "VignetteBuilder": "knitr", "Config/pak/sysreqs": "zlib1g-dev", "Repository": "https://bioc.r-universe.dev", "Date/Publication": "2026-04-28 12:55:53 UTC", "RemoteUrl": "https://github.com/bioc/awst", "RemoteRef": "HEAD", "RemoteSha": "c693f862908ad025a3a1220f0a0528293bf25006", "NeedsCompilation": "no", "Packaged": { "Date": "2026-06-21 09:13:33 UTC", "User": "root" }, "Author": "Davide Risso [aut, cre, cph] 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