Package: RLassoCox 1.13.0
Wei Liu
RLassoCox: A reweighted Lasso-Cox by integrating gene interaction information
RLassoCox is a package that implements the RLasso-Cox model proposed by Wei Liu. The RLasso-Cox model integrates gene interaction information into the Lasso-Cox model for accurate survival prediction and survival biomarker discovery. It is based on the hypothesis that topologically important genes in the gene interaction network tend to have stable expression changes. The RLasso-Cox model uses random walk to evaluate the topological weight of genes, and then highlights topologically important genes to improve the generalization ability of the Lasso-Cox model. The RLasso-Cox model has the advantage of identifying small gene sets with high prognostic performance on independent datasets, which may play an important role in identifying robust survival biomarkers for various cancer types.
Authors:
RLassoCox_1.13.0.tar.gz
RLassoCox_1.13.0.zip(r-4.5)RLassoCox_1.13.0.zip(r-4.4)RLassoCox_1.13.0.zip(r-4.3)
RLassoCox_1.13.0.tgz(r-4.4-any)RLassoCox_1.13.0.tgz(r-4.3-any)
RLassoCox_1.13.0.tar.gz(r-4.5-noble)RLassoCox_1.13.0.tar.gz(r-4.4-noble)
RLassoCox_1.13.0.tgz(r-4.4-emscripten)RLassoCox_1.13.0.tgz(r-4.3-emscripten)
RLassoCox.pdf |RLassoCox.html✨
RLassoCox/json (API)
NEWS
| # Install 'RLassoCox' in R: |
| install.packages('RLassoCox', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org')) |
Bug tracker:https://github.com/weiliu123/rlassocox/issues
- dGMMirGraph - The KEGG network
- mRNA_matrix - The expression data
- survData - Survival data
On BioConductor:RLassoCox-1.13.0(bioc 3.20)RLassoCox-1.12.0(bioc 3.19)
Last updated 2 months agofrom:04330c08fb
Exports:cvRLassoCoxpredict.cvRLassoCoxpredict.RLassoCoxRLassoCox
Dependencies:clicodetoolscpp11foreachglmnetglueigraphiteratorslatticelifecyclemagrittrMatrixpkgconfigRcppRcppEigenrlangshapesurvivalvctrs
Readme and manuals
Help Manual
| Help page | Topics |
|---|---|
| A reweighted Lasso-Cox by integrating gene interaction information | RLassoCox-package |
| Cross-validation for the RLasso-Cox model | cvRLassoCox |
| The KEGG network | dGMMirGraph |
| The expression data | mRNA_matrix |
| Make predictions from a cross-validated RLasso-Cox model | predict.cvRLassoCox |
| Make predictions from a RLasso-Cox model | predict.RLassoCox |
| Reweighted Lasso-Cox model | RLassoCox |
| Directed Random Walk | rw |
| Survival data | survData |
