Package: NetPathMiner 1.43.1

Ahmed Mohamed

NetPathMiner: NetPathMiner for Biological Network Construction, Path Mining and Visualization

NetPathMiner is a general framework for network path mining using genome-scale networks. It constructs networks from KGML, SBML and BioPAX files, providing three network representations, metabolic, reaction and gene representations. NetPathMiner finds active paths and applies machine learning methods to summarize found paths for easy interpretation. It also provides static and interactive visualizations of networks and paths to aid manual investigation.

Authors:Ahmed Mohamed [aut, cre], Tim Hancock [aut], Tim Hancock [aut]

NetPathMiner_1.43.1.tar.gz

NetPathMiner_1.43.1.tgz(r-4.4-x86_64)NetPathMiner_1.43.1.tgz(r-4.4-arm64)NetPathMiner_1.43.1.tgz(r-4.3-x86_64)NetPathMiner_1.43.1.tgz(r-4.3-arm64)
NetPathMiner_1.43.1.tar.gz(r-4.5-noble)NetPathMiner_1.43.1.tar.gz(r-4.4-noble)
NetPathMiner.pdf |NetPathMiner.html
NetPathMiner/json (API)
NEWS

# Install 'NetPathMiner' in R:
install.packages('NetPathMiner', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Bug tracker:https://github.com/ahmohamed/netpathminer/issues

Uses libs:
  • libsbml– System Biology Markup Language library
  • libxml2– GNOME XML library
  • openblas– Optimized BLAS
  • c++– GNU Standard C++ Library v3
Datasets:

On BioConductor:NetPathMiner-1.43.0(bioc 3.21)NetPathMiner-1.42.0(bioc 3.20)

graphandnetworkpathwaysnetworkclusteringclassificationlibsbmllibxml2openblascpp

6.53 score 7 stars 9 scripts 218 downloads 2 mentions 44 exports 11 dependencies

Last updated 22 days agofrom:b338534ea5. Checks:OK: 1 NOTE: 5. Indexed: yes.

TargetResultDate
Doc / VignettesOKNov 28 2024
R-4.5-linux-x86_64NOTENov 28 2024
R-4.4-mac-x86_64NOTENov 28 2024
R-4.4-mac-aarch64NOTENov 28 2024
R-4.3-mac-x86_64NOTENov 28 2024
R-4.3-mac-aarch64NOTENov 28 2024

Exports:assignEdgeWeightsbiopax2igraphcolorVertexByAttrexpandComplexesextractPathNetworkfetchAttributegetAttributegetAttrNamesgetAttrStatusgetGeneSetNetworksgetGeneSetsgetPathsAsEIDsKGML2igraphlayoutVertexByAttrmakeGeneNetworkmakeMetaboliteNetworkmakeReactionNetworkNPMdefaultspathClassifierpathClusterpathRankerpathsToBinaryplotAllNetworksplotClassifierROCplotClusterMatrixplotClusterProbsplotClustersplotCytoscapeGMLplotNetworkplotPathClassifierplotPathClusterplotPathspredictPathClassifierpredictPathClusterregisterMemoryErrreindexNetworkrmAttributermSmallCompoundsSBML2igraphsetAttributesimplifyReactionNetworkstdAttrNamestoGraphNELvertexDeleteReconnect

Dependencies:clicpp11glueigraphlatticelifecyclemagrittrMatrixpkgconfigrlangvctrs

Workflow for NetPathMiner

Rendered fromNPMVignette.Rmdusingknitr::rmarkdownon Nov 28 2024.

Last update: 2019-04-01
Started: 2019-03-02

Readme and manuals

Help Manual

Help pageTopics
General framework for network extraction, path mining.NetPathMiner-package NetPathMiner NPM
Assigning weights to network edgesassignEdgeWeights
Processes BioPAX objects into igraph objectsbiopax2igraph
Computes colors for vertices according to their attributes.colorVertexByAttr
Biopax example dataex_biopax
Singaling network from KGML exampleex_kgml_sig
An microarray data example.ex_microarray
Metabolic network from SBML exampleex_sbml
Expand reactions / complexes into their gene constituents.expandComplexes makeGeneNetwork
Creates a subnetwork from a ranked path listextractPathNetwork
Get / Set vertex attribute names and coveragegetAttribute getAttrNames getAttrStatus rmAttribute setAttribute
Generate geneset networks from an annotated network.getGeneSetNetworks
Generate genesets from an annotated network.getGeneSets
Convert a ranked path list to edge ids of a graphgetPathsAsEIDs
Processes KGML files into igraph objectsKGML2igraph
A graph layout function, which groups vertices by attribute.layoutVertexByAttr
Convert metabolic network to metabolite network.makeMetaboliteNetwork
Convert metabolic network to reaction network.makeReactionNetwork
Default values for NetPathMinerNPMdefaults
HME3M Markov pathway classifier.pathClassifier
3M Markov mixture model for clustering pathwayspathCluster
Extracting and ranking paths from a networkpathRanker
Converts the result from pathRanker into something suitable for pathClassifier or pathCluster.pathsToBinary
Higlighting ranked paths over multiple network representations.plotAllNetworks
Diagnostic plots for pathClassifier.plotClassifierROC
Plots the structure of all path clustersplotClusterMatrix plotClusterProbs plotClusters
Plots an annotated igraph object in Cytoscape.plotCytoscapeGML
Plots an annotated igraph object.plotNetwork
Plots the structure of specified path found by pathClassifier.plotPathClassifier
Plots the structure of specified path clusterplotPathCluster
Plots an annotated igraph object higlighting ranked paths.plotPaths
Predicts new paths given a pathClassifier model.predictPathClassifier
Predicts new paths given a pathCluster modelpredictPathCluster
Internal method to register memery errors.registerMemoryErr
Replaces current vertex ids with chosen attribute.reindexNetwork
Remove uniquitous compounds from a metabolic networkrmSmallCompounds
Processes SBML files into igraph objectsSBML2igraph
Removes reactions with no gene annotationssimplifyReactionNetwork
MIRIAM annotation attributesfetchAttribute stdAttrNames
Converts an annotated igraph object to graphNELtoGraphNEL
Network editing: removing vertices and connecting their neighboursvertexDeleteReconnect