Package: sigsquared 1.39.0

UnJin Lee

sigsquared: Gene signature generation for functionally validated signaling pathways

By leveraging statistical properties (log-rank test for survival) of patient cohorts defined by binary thresholds, poor-prognosis patients are identified by the sigsquared package via optimization over a cost function reducing type I and II error.

Authors:UnJin Lee

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sigsquared.pdf |sigsquared.html
sigsquared/json (API)

# Install 'sigsquared' in R:
install.packages('sigsquared', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))
Datasets:
  • BrCa443 - Breast Cancer 443 Data Set

On BioConductor:sigsquared-1.39.0(bioc 3.21)sigsquared-1.38.0(bioc 3.20)

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

3.30 score 1 scripts 260 downloads 10 exports 6 dependencies

Last updated 4 months agofrom:1fece7e65b. Checks:1 OK, 7 NOTE. Indexed: yes.

TargetResultLatest binary
Doc / VignettesOKFeb 16 2025
R-4.5-winNOTEFeb 16 2025
R-4.5-macNOTEFeb 16 2025
R-4.5-linuxNOTEFeb 16 2025
R-4.4-winNOTEFeb 16 2025
R-4.4-macNOTEFeb 16 2025
R-4.3-winNOTEFeb 16 2025
R-4.3-macNOTEFeb 16 2025

Exports:analysisPipelineensembleAdjustablegetDirectgetGenesgetNGenesgetThresholdssetDirectsetGenessetGeneSignaturesetThresholds

Dependencies:BiobaseBiocGenericsgenericslatticeMatrixsurvival

SigSquared

Rendered fromsigsquared.Rnwusingutils::Sweaveon Feb 16 2025.

Last update: 2015-02-28
Started: 2015-02-28

Readme and manuals

Help Manual

Help pageTopics
Training of thresholdsanalysisPipeline
Breast Cancer 443 Data SetBrCa443
Application of geneSignature objectensembleAdjustable
Class '"geneSignature"'analysisPipeline,ExpressionSet,geneSignature-method ensembleAdjustable,ExpressionSet,geneSignature-method ensembleAdjustable,matrix,geneSignature-method geneSignature-class getDirect,geneSignature-method getGenes,geneSignature-method getGenes,solnSpace-method getNGenes,geneSignature-method getThresholds,geneSignature-method getThresholds,solnSpace-method setDirect,geneSignature,numeric-method setGenes,geneSignature-method setGenes,solnSpace-method setGeneSignature,geneSignature-method setThresholds,geneSignature-method setThresholds,solnSpace-method
geneSignature functionsgetDirect getGenes getNGenes getThresholds setDirect setGenes setGeneSignature setThresholds
The sigsquared packagesigsquared