Package: orthos 1.3.0
Panagiotis Papasaikas
orthos: `orthos` is an R package for variance decomposition using conditional variational auto-encoders
`orthos` decomposes RNA-seq contrasts, for example obtained from a gene knock-out or compound treatment experiment, into unspecific and experiment-specific components. Original and decomposed contrasts can be efficiently queried against a large database of contrasts (derived from ARCHS4, https://maayanlab.cloud/archs4/) to identify similar experiments. `orthos` furthermore provides plotting functions to visualize the results of such a search for similar contrasts.
Authors:
orthos_1.3.0.tar.gz
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orthos.pdf |orthos.html✨
orthos/json (API)
NEWS
| # Install 'orthos' in R: |
| install.packages('orthos', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org')) |
On BioConductor:orthos-1.3.0(bioc 3.20)orthos-1.2.0(bioc 3.19)
This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.
Last updated 2 months agofrom:ef3a3ea9f9
Exports:decomposeVarloadContrastDatabaseplotQueryResultsManhplotQueryResultsViolinqueryWithContraststestOrthosEnv
Dependencies:abindAnnotationDbiAnnotationHubaskpassbackportsbase64encbasiliskbasilisk.utilsBHBiobaseBiocFileCacheBiocGenericsBiocManagerBiocParallelBiocVersionBiostringsbitbit64blobbootbroomcachemcarcarDataclicodetoolscolorspaceconfigcorrplotcowplotcpp11crayoncurlDBIdbplyrDelayedArrayDerivdir.expirydoBydplyrExperimentHubfansifarverfastmapfilelockformatRfutile.loggerfutile.optionsgenericsGenomeInfoDbGenomeInfoDbDataGenomicRangesggplot2ggpubrggrepelggsciggsignifgluegridExtragtableHDF5ArrayherehttrIRangesisobandjsonliteKEGGRESTkeraslabelinglambda.rlatticelifecyclelme4magrittrMASSMatrixMatrixGenericsMatrixModelsmatrixStatsmemoisemgcvmicrobenchmarkmimeminqamodelrmunsellnlmenloptrnnetnumDerivopensslorthosDatapbkrtestpillarpkgconfigplogrplyrpngpolynomprocessxpspurrrquantregR6rappdirsRColorBrewerRcppRcppEigenRcppTOMLreticulaterhdf5rhdf5filtersRhdf5librlangrprojrootRSQLiterstatixrstudioapiS4ArraysS4VectorsscalessnowSparseArraySparseMstringistringrSummarizedExperimentsurvivalsystensorflowtfautographtfrunstibbletidyrtidyselectUCSC.utilsutf8vctrsviridisLitewhiskerwithrXVectoryamlzeallotzlibbioc
Readme and manuals
Help Manual
| Help page | Topics |
|---|---|
| orthos - variance decomposition using conditional variational auto-encoders | orthos-package orthos |
| Decompose input contrasts to decoded and residual fractions | decomposeVar |
| Load contrast database | loadContrastDatabase |
| Visualize query results as a composite manhattan/density plot. | plotQueryResultsManh |
| Visualize query results as violin plots | plotQueryResultsViolin |
| Query the contrast database with a set of contrasts | queryWithContrasts |
| Test conda environment | testOrthosEnv |