Package: mosaics 2.45.0

Dongjun Chung

mosaics: MOSAiCS (MOdel-based one and two Sample Analysis and Inference for ChIP-Seq)

This package provides functions for fitting MOSAiCS and MOSAiCS-HMM, a statistical framework to analyze one-sample or two-sample ChIP-seq data of transcription factor binding and histone modification.

Authors:Dongjun Chung, Pei Fen Kuan, Rene Welch, Sunduz Keles

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mosaics.pdf |mosaics.html
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NEWS

# Install 'mosaics' in R:
install.packages('mosaics', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Uses libs:
  • c++– GNU Standard C++ Library v3

On BioConductor:mosaics-2.45.0(bioc 3.21)mosaics-2.44.0(bioc 3.20)

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

chipseqsequencingtranscriptiongeneticsbioinformaticscpp

3.30 score 8 scripts 438 downloads 31 exports 45 dependencies

Last updated 2 months agofrom:43771c2f4f. Checks:OK: 9. Indexed: yes.

TargetResultDate
Doc / VignettesOKNov 29 2024
R-4.5-win-x86_64OKNov 29 2024
R-4.5-linux-x86_64OKNov 29 2024
R-4.4-win-x86_64OKNov 29 2024
R-4.4-mac-x86_64OKNov 29 2024
R-4.4-mac-aarch64OKNov 29 2024
R-4.3-win-x86_64OKNov 29 2024
R-4.3-mac-x86_64OKNov 29 2024
R-4.3-mac-aarch64OKNov 29 2024

Exports:adjustBoundarybdBinchrIDconstructBinsconv_1Sconv_2ScoordempFDRestimatesexportextractReadsfilterPeakfindSummitgcContentgenerateWiginputmappabilitymosaicsFitmosaicsFitHMMmosaicsPeakmosaicsPeakHMMmosaicsRunAllplotpostProbprintreadreadBinsreadCoverageseqDepthshowtagCount

Dependencies:abindaskpassBHBiobaseBiocGenericsBiocParallelBiostringsbitopscodetoolscpp11crayoncurlDelayedArrayformatRfutile.loggerfutile.optionsgenericsGenomeInfoDbGenomeInfoDbDataGenomicAlignmentsGenomicRangeshttrIRangesjsonlitelambda.rlatticeMASSMatrixMatrixGenericsmatrixStatsmimeopensslR6RcppRhtslibRsamtoolsS4ArraysS4VectorssnowSparseArraySummarizedExperimentsysUCSC.utilsXVectorzlibbioc

MOSAiCS

Rendered frommosaics-example.Rnwusingutils::Sweaveon Nov 29 2024.

Last update: 2016-08-11
Started: 2013-11-01

Readme and manuals

Help Manual

Help pageTopics
MOSAiCS (MOdel-based one and two Sample Analysis and Inference for ChIP-Seq)mosaics-package mosaics
Adjust boundaries of peak regionsadjustBoundary adjustBoundary,MosaicsPeak-method
Class "BinData"BinData-class chrID chrID,BinData-method coord coord,BinData-method gcContent gcContent,BinData-method input input,BinData-method mappability mappability,BinData-method plot,BinData,missing-method print,BinData-method seqDepth seqDepth,BinData-method show,BinData-method tagCount tagCount,BinData-method
Construct bin-level ChIP-sep data from an aligned read fileconstructBins
Extract estimates of the fitted MOSAiCS modelestimates estimates,MosaicsFit-method
Export peak calling results to text filesexport export,MosaicsPeak-method
Load read-level data and extract reads corresponding to each peak regionextractReads extractReads,MosaicsPeak-method
Filter out potentially false positive peaksfilterPeak filterPeak,MosaicsPeak-method
Find a summit for each peak regionfindSummit findSummit,MosaicsPeak-method
Construct wiggle files from an aligned ChIP-sep read filegenerateWig
Fit MOSAiCS modelmosaicsFit mosaicsFit,BinData-method
Class "MosaicsFit"MosaicsFit-class plot,MosaicsFit,ANY-method print,MosaicsFit-method seqDepth,MosaicsFit-method show,MosaicsFit-method
Class "MosaicsFitEst"MosaicsFitEst-class
Fit MOSAiCS-HMM modelmosaicsFitHMM mosaicsFitHMM,MosaicsFit-method
Class "MosaicsFitParam"MosaicsFitParam-class
Class "MosaicsHMM"estimates,MosaicsHMM-method MosaicsHMM-class plot,MosaicsHMM,missing-method print,MosaicsHMM-method seqDepth,MosaicsHMM-method show,MosaicsHMM-method
Call peaks using fitted MOSAiCS modelmosaicsPeak mosaicsPeak,MosaicsFit-method
Class "MosaicsPeak"bdBin bdBin,MosaicsPeak-method empFDR empFDR,MosaicsPeak-method MosaicsPeak-class plot,MosaicsPeak,missing-method postProb postProb,MosaicsPeak-method print,MosaicsPeak-method read read,MosaicsPeak-method readCoverage readCoverage,MosaicsPeak-method seqDepth,MosaicsPeak-method show,MosaicsPeak-method
Call broad peaks using fitted MOSAiCS-HMM modelmosaicsPeakHMM mosaicsPeakHMM,MosaicsHMM-method
Class "MosaicsPeakParam"MosaicsPeakParam-class
Analyze ChIP-seq data using the MOSAiCS frameworkmosaicsRunAll
Import bin-level ChIP-sep datareadBins
Class "TagData"TagData-class