Package: minfi 1.53.1

Kasper Daniel Hansen

minfi: Analyze Illumina Infinium DNA methylation arrays

Tools to analyze & visualize Illumina Infinium methylation arrays.

Authors:Kasper Daniel Hansen [cre, aut], Martin Aryee [aut], Rafael A. Irizarry [aut], Andrew E. Jaffe [ctb], Jovana Maksimovic [ctb], E. Andres Houseman [ctb], Jean-Philippe Fortin [ctb], Tim Triche [ctb], Shan V. Andrews [ctb], Peter F. Hickey [ctb]

minfi_1.53.1.tar.gz
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minfi.pdf |minfi.html
minfi/json (API)
NEWS

# Install 'minfi' in R:
install.packages('minfi', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Bug tracker:https://github.com/hansenlab/minfi/issues

On BioConductor:minfi-1.53.0(bioc 3.21)minfi-1.52.0(bioc 3.20)

immunooncologydnamethylationdifferentialmethylationepigeneticsmicroarraymethylationarraymultichanneltwochanneldataimportnormalizationpreprocessingqualitycontrol

13.12 score 60 stars 34 packages 1.1k scripts 4.4k downloads 506 mentions 95 exports 134 dependencies

Last updated 4 days agofrom:3852366c4f. Checks:OK: 1 ERROR: 1 NOTE: 5. Indexed: yes.

TargetResultDate
Doc / VignettesOKNov 20 2024
R-4.5-winNOTENov 20 2024
R-4.5-linuxERRORNov 20 2024
R-4.4-winNOTENov 20 2024
R-4.4-macNOTENov 20 2024
R-4.3-winNOTENov 20 2024
R-4.3-macNOTENov 20 2024

Exports:addQCaddSexaddSnpInfoannotationannotation<-bgcorrect.illuminablockFinderbumphuntercoercecombinecombineArrayscompartmentscontrolStripPlotconvertArraycpgCollapsecreateCorMatrixdensityBeanPlotdensityPlotdetectionPdmpFinderdropLociWithSnpsdropMethylationLociestimateCellCountsextractABfeatureNamesfeatureNames<-fixMethOutliersgaphunterGenomicMethylSetGenomicRatioSetgetAnnotationgetAnnotationObjectgetBetagetCNgetControlAddressgetGenomicRatioSetFromGEOgetGreengetIslandStatusgetLocationsgetMgetManifestgetManifestInfogetMethgetMethSignalgetNBeadsgetOOBgetProbeInfogetProbeTypegetQCgetRedgetSexgetSnpBetagetSnpInfogetUnmethIlluminaMethylationAnnotationIlluminaMethylationManifestilogit2initializelogit2makeGenomicRatioSetFromMatrixmapToGenomemdsPlotMethylSetminfiQCnormalize.illumina.controlpDatapData<-plotBetasByTypeplotCpgplotQCplotSexpreprocessFunnormpreprocessIlluminapreprocessMethodpreprocessNoobpreprocessQuantilepreprocessRawpreprocessSWANqcReportratioConvertRatioSetread.450kread.450k.expread.450k.sheetread.metharrayread.metharray.expread.metharray.sheetreadGEORawFilereadTCGARGChannelSetRGChannelSetExtendedsampleNamessampleNames<-showsubsetByLoci

Dependencies:abindannotateAnnotationDbiaskpassbase64beanplotBHBiobaseBiocGenericsBiocIOBiocParallelBiostringsbitbit64bitopsblobbumphuntercachemclicliprcodetoolscpp11crayoncurldata.tableDBIDelayedArrayDelayedMatrixStatsdigestdoRNGdplyrfansifastmapforeachformatRfutile.loggerfutile.optionsgenefiltergenericsGenomeInfoDbGenomeInfoDbDataGenomicAlignmentsGenomicFeaturesGenomicRangesGEOqueryglueHDF5Arrayhmshttrhttr2illuminaioIRangesiteratorsjsonliteKEGGRESTlambda.rlatticelifecyclelimmalocfitmagrittrMASSMatrixMatrixGenericsmatrixStatsmclustmemoisemimemulttestnlmenor1mixopensslpillarpkgconfigplogrplyrpngpreprocessCoreprettyunitsprogresspurrrquadprogR.methodsS3R.ooR.utilsR6rappdirsRColorBrewerRcppRCurlreadrrentrezreshaperestfulrrhdf5rhdf5filtersRhdf5libRhtslibrjsonrlangrngtoolsRsamtoolsRSQLitertracklayerrvestS4ArraysS4VectorsscrimeselectrsiggenessnowSparseArraysparseMatrixStatsstatmodstringistringrSummarizedExperimentsurvivalsystibbletidyrtidyselecttzdbUCSC.utilsutf8vctrsvroomwithrXMLxml2xtableXVectoryamlzlibbioc

The minfi User's Guide

Rendered fromminfi.Rmdusingknitr::rmarkdownon Nov 20 2024.

Last update: 2017-10-16
Started: 2016-03-21

Readme and manuals

Help Manual

Help pageTopics
Analyze Illumina's methylation arraysminfi-package minfi
Finds blocks of methylation differences for Illumina methylation arraysblockFinder
Methods for function 'bumphunter' in Package 'minfi'bumphunter,GenomicRatioSet-method
A method for combining different types of methylation arrays into a virtual array.combineArrays combineArrays,GenomicMethylSet,GenomicMethylSet-method combineArrays,GenomicRatioSet,GenomicRatioSet-method combineArrays,MethylSet,MethylSet-method combineArrays,RatioSet,RatioSet-method combineArrays,RGChannelSet,RGChannelSet-method
Estimates A/B compartments from Illumina methylation arrayscompartments createCorMatrix extractAB
Plot control probe signals.controlStripPlot
A method for converting a type of methylation arrays into a virtual array of another type.convertArray convertArray,GenomicMethylSet-method convertArray,GenomicRatioSet-method convertArray,MethylSet-method convertArray,RatioSet-method convertArray,RGChannelSet-method
Collapse methylation values of adjacent CpGs into a summary value.cpgCollapse
Density bean plots of methylation Beta values.densityBeanPlot
Density plots of methylation Beta values.densityPlot
Detection p-values for all probed genomic positions.detectionP
Find differentially methylated positionsdmpFinder
Cell Proportion EstimationestimateCellCounts
Fix methylation outliersfixMethOutliers
Find gap signals in 450k datagaphunter
GenomicMethylSet instancesannotation,GenomicMethylSet-method annotation<-,GenomicMethylSet,ANY-method combine,GenomicMethylSet,GenomicMethylSet-method featureNames,GenomicMethylSet-method featureNames<-,GenomicMethylSet-method GenomicMethylSet GenomicMethylSet-class getBeta,GenomicMethylSet-method getCN,GenomicMethylSet-method getM,GenomicMethylSet-method getMeth,GenomicMethylSet-method getUnmeth,GenomicMethylSet-method mapToGenome,GenomicMethylSet-method pData,GenomicMethylSet-method pData<-,GenomicMethylSet,DataFrame-method preprocessMethod,GenomicMethylSet-method sampleNames,GenomicMethylSet-method sampleNames<-,GenomicMethylSet,ANY-method show,GenomicMethylSet-method
GenomicRatioSet instancesannotation,GenomicRatioSet-method annotation<-,GenomicRatioSet,ANY-method combine,GenomicRatioSet,GenomicRatioSet-method featureNames,GenomicRatioSet-method featureNames<-,GenomicRatioSet-method GenomicRatioSet GenomicRatioSet-class getBeta,GenomicRatioSet-method getCN getCN,GenomicRatioSet-method getM,GenomicRatioSet-method mapToGenome,GenomicRatioSet-method pData,GenomicRatioSet-method pData<-,GenomicRatioSet,DataFrame-method preprocessMethod,GenomicRatioSet-method sampleNames,GenomicRatioSet-method sampleNames<-,GenomicRatioSet,ANY-method show,GenomicRatioSet-method
Accessing annotation for Illumina methylation objectsaddSnpInfo dropLociWithSnps getAnnotation getAnnotationObject getIslandStatus getLocations getProbeType getSnpInfo
Reading Illumina methylation array data from GEO.getGenomicRatioSetFromGEO
Various utilitiesgetMethSignal
Estimate sample-specific quality control (QC) for methylation dataaddQC getQC plotQC
Estimating sample sex based on methylation dataaddSex getSex plotSex
Class 'IlluminaMethylationAnnotation'getManifest,IlluminaMethylationAnnotation-method IlluminaMethylationAnnotation IlluminaMethylationAnnotation-class show,IlluminaMethylationAnnotation-method
Class '"IlluminaMethylationManifest"'getControlAddress getManifest getManifest,character-method getManifest,IlluminaMethylationManifest-method getManifestInfo getProbeInfo IlluminaMethylationManifest IlluminaMethylationManifest-class show,IlluminaMethylationManifest-method
logit in base 2.ilogit2 logit2
Make a GenomicRatioSet from a matrixmakeGenomicRatioSetFromMatrix
Mapping methylation data to the genomemapToGenome mapToGenome,MethylSet-method mapToGenome,RatioSet-method mapToGenome,RGChannelSet-method mapToGenome-methods
Multi-dimensional scaling plots giving an overview of similarities and differences between samples.mdsPlot
MethylSet instancesannotation,MethylSet-method annotation<-,MethylSet,ANY-method combine,MethylSet,MethylSet-method dropMethylationLoci featureNames,MethylSet-method featureNames<-,MethylSet-method getBeta getBeta,MethylSet-method getCN,MethylSet-method getM getM,MethylSet-method getManifest,MethylSet-method getMeth getMeth,MethylSet-method getUnmeth getUnmeth,MethylSet-method MethylSet MethylSet-class pData,MethylSet-method pData<-,MethylSet,DataFrame-method preprocessMethod preprocessMethod,MethylSet-method sampleNames,MethylSet-method sampleNames<-,MethylSet,ANY-method show,MethylSet-method
Defunct functions in package 'minfi'minfi-defunct read.450k read.450k.exp read.450k.sheet
Deprecated functions in package 'minfi'minfi-deprecated
easy one-step QC of methylation objectminfiQC
Plot the overall distribution of beta values and the distributions of the Infinium I and II probe types.plotBetasByType
Plot methylation values at an single genomic positionplotCpg
Functional normalization for Illumina 450k arrayspreprocessFunnorm
Perform preprocessing as Genome Studio.bgcorrect.illumina normalize.illumina.control preprocessIllumina
The Noob/ssNoob preprocessing method for Infinium methylation microarrays.preprocessNoob
Stratified quantile normalization for an Illumina methylation array.preprocessQuantile
Creation of a MethylSet without normalizationpreprocessRaw
Subset-quantile Within Array Normalisation for Illumina Infinium HumanMethylation450 BeadChipspreprocessSWAN
QC report for Illumina Infinium Human Methylation 450k arraysqcReport
Converting methylation signals to ratios (Beta or M-values)ratioConvert ratioConvert,GenomicMethylSet-method ratioConvert,MethylSet-method ratioConvert-methods
RatioSet instancesannotation,RatioSet-method annotation<-,RatioSet,ANY-method combine,RatioSet,RatioSet-method featureNames,RatioSet-method featureNames<-,RatioSet-method getBeta,RatioSet-method getCN,RatioSet-method getM,RatioSet-method pData,RatioSet-method pData<-,RatioSet,DataFrame-method preprocessMethod,RatioSet-method RatioSet RatioSet-class sampleNames,RatioSet-method sampleNames<-,RatioSet,ANY-method show,RatioSet-method
Parsing IDAT files from Illumina methylation arrays.read.metharray
Reads an entire metharray experiment using a sample sheetread.metharray.exp
Reading an Illumina methylation sample sheetread.metharray.sheet
Read in Unmethylated and Methylated signals from a GEO raw file.readGEORawFile
Read in tab deliminited file in the TCGA formatreadTCGA
Class '"RGChannelSet"'annotation,RGChannelSet-method annotation<-,RGChannelSet,ANY-method coerce,RGChannelSetExtended,RGChannelSet-method combine,RGChannelSet,RGChannelSet-method featureNames,RGChannelSet-method featureNames<-,RGChannelSet-method getBeta,RGChannelSet-method getGreen getManifest,RGChannelSet-method getNBeads getOOB getRed getSnpBeta pData,RGChannelSet-method pData<-,RGChannelSet,DataFrame-method RGChannelSet RGChannelSet-class RGChannelSetExtended RGChannelSetExtended-class sampleNames,RGChannelSet-method sampleNames<-,RGChannelSet,ANY-method show,RGChannelSet-method
Subset an RGChannelset by CpG loci.subsetByLoci