Package: drugfindR 1.1.0

Ali Sajid Imami

drugfindR: Investigate iLINCS for candidate repurposable drugs

This package provides a convenient way to access the LINCS Signatures available in the iLINCS database. These signatures include Consensus Gene Knockdown Signatures, Gene Overexpression signatures and Chemical Perturbagen Signatures. It also provides a way to enter your own transcriptomic signatures and identify concordant and discordant signatures in the LINCS database.

Authors:Ali Sajid Imami [aut, cre], Smita Sahay [aut], Justin Fortune Creeden [aut], Robert Erne McCullumsmith [ctb, fnd]

drugfindR_1.1.0.tar.gz
drugfindR_1.1.0.zip(r-4.7)drugfindR_1.1.0.zip(r-4.6)drugfindR_1.1.0.zip(r-4.5)
drugfindR_1.1.0.tgz(r-4.6-any)drugfindR_1.1.0.tgz(r-4.5-any)
drugfindR_1.1.0.tar.gz(r-4.7-any)drugfindR_1.1.0.tar.gz(r-4.6-any)
drugfindR_1.1.0.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
card.svg |card.png
drugfindR/json (API)
NEWS

# Install 'drugfindR' in R:

install.packages('drugfindR', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/cogdisreslab/drugfindr/issues

Pkgdown/docs site:https://cogdisreslab.github.io

On BioConductor:drugfindR-1.1.0(bioc 3.24)drugfindR-1.0.0(bioc 3.23)

lincs ilincs drug repurposing drug discovery transcriptomics gene expression gene knockdown gene overexpression chemical perturbagen drugfindr bioinformatics bioinformatics-pipeline

7.18 score 10 stars 151 scripts 179 downloads 7 exports 38 dependencies

Last updated from:8b653fc885. Checks:1 NOTE, 9 OK. Indexed: yes.

Target	Result	Time
bioc-checks	NOTE	191
linux-devel-x86_64	OK	263
source / vignettes	OK	307
linux-release-x86_64	OK	299
macos-release-arm64	OK	161
macos-oldrel-arm64	OK	141
windows-devel	OK	142
windows-release	OK	151
windows-oldrel	OK	179
wasm-release	OK	137

Exports:consensusConcordants filterSignature getConcordants getSignature investigateSignature investigateTarget prepareSignature

Dependencies:askpass BiocGenerics bit bit64 cli clipr cpp11 crayon curl DFplyr dplyr generics glue hms httr2 lifecycle magrittr openssl pillar pkgconfig prettyunits progress purrr R6 rappdirs readr rlang S4Vectors stringi stringr sys tibble tidyselect tzdb utf8 vctrs vroom withr

drugfindR

Rendered fromdrugfindR.Rmdusingknitr::rmarkdownon May 30 2026.

Last update: 2025-12-14
Started: 2023-01-29

Citation

Development and contributors

Readme and manuals

Help Manual

Help page	Topics
Generate a Consensus list of Targets [Stable]	consensusConcordants
Filter the L1000 Signature [Stable]	filterSignature
Get concordant signatures from iLINCS database [Stable]	getConcordants
Get the L1000 Signature from iLINCS [Stable]	getSignature
Investigate a given DGE dataset [Stable]	investigateSignature
Investigate concordant signatures for a gene or drug [Stable]	investigateTarget
Prepare an L1000 Signature from a given differential gene expression output [Stable]	prepareSignature