Package: drugTargetInteractions 1.13.0

Thomas Girke

drugTargetInteractions: Drug-Target Interactions

Provides utilities for identifying drug-target interactions for sets of small molecule or gene/protein identifiers. The required drug-target interaction information is obained from a local SQLite instance of the ChEMBL database. ChEMBL has been chosen for this purpose, because it provides one of the most comprehensive and best annotatated knowledge resources for drug-target information available in the public domain.

Authors:Thomas Girke [cre, aut]

# Install 'drugTargetInteractions' in R:

install.packages('drugTargetInteractions', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/girke-lab/drugtargetinteractions/issues

On BioConductor:drugTargetInteractions-1.13.0(bioc 3.20)drugTargetInteractions-1.12.0(bioc 3.19)

bioconductor-package

14 exports 0.61 score 100 dependencies

Last updated 2 months agofrom:6c1c6dc989

Exports:cmpIdMapping downloadChemblDb downloadUniChem drugTargetAnnot drugTargetAnnotTable drugTargetBioactivity genConfig getDrugTarget getParalogs getSymEnsUp getUniprotIDs processDrugage runDrugTarget_Annot_Bioassay transformTTD

Dependencies:abind AnnotationDbi AnnotationFilter askpass BH Biobase BiocBaseUtils BiocFileCache BiocGenerics BiocIO BiocParallel biomaRt Biostrings bit bit64 bitops blob cachem cli codetools cpp11 crayon curl DBI dbplyr DelayedArray digest dplyr ensembldb fansi fastmap filelock formatR futile.logger futile.options generics GenomeInfoDb GenomeInfoDbData GenomicAlignments GenomicFeatures GenomicRanges glue hms httpcache httr httr2 IRanges jsonlite KEGGREST lambda.r lattice lazyeval lifecycle magrittr Matrix MatrixGenerics matrixStats memoise mime openssl pillar pkgconfig plogr png prettyunits progress ProtGenerics purrr R6 rappdirs RCurl restfulr Rhtslib rjson rjsoncons rlang Rsamtools RSQLite rtracklayer S4Arrays S4Vectors snow SparseArray stringi stringr SummarizedExperiment sys tibble tidyr tidyselect UCSC.utils UniProt.ws utf8 vctrs withr XML xml2 XVector yaml zlibbioc

Drug-Target Interactions

Authors: Kevin Horan, Yuzhu Duan, Austin Leong, Dan Evans, Jamison McCorrison, Nicholas Schork and Thomas Girke

Rendered fromdrugTargetInteractions.Rmdusingknitr::rmarkdownon Jun 26 2024.

Last update: 2021-08-26
Started: 2020-11-30

Help page	Topics
Drug-Target Interactions	drugTargetInteractions-package drugTargetInteractions
cmpIdMapping	cmpIdMapping
downloadChemblDb	downloadChemblDb
downloadUniChem	downloadUniChem
drugTargetAnnot	drugTargetAnnot queryBy
drugTargetAnnotTable	drugTargetAnnotTable
drugTargetBioactivity	drugTargetBioactivity
genConfig	genConfig
getDrugTarget	getDrugTarget
getParalogs	getParalogs
Gene to Protein ID Mappings	getSymEnsUp
Retrieve UniProt IDs via ID and Cluster Mappings	getUniprotIDs
processDrugage	processDrugage
runDrugTarget_Annot_Bioassay	runDrugTarget_Annot_Bioassay
transformTTD	transformTTD

Package: drugTargetInteractions 1.13.0

drugTargetInteractions: Drug-Target Interactions

Drug-Target Interactions

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