Package: destiny 3.19.0

Philipp Angerer

destiny: Creates diffusion maps

Create and plot diffusion maps.

Authors:Philipp Angerer [cre, aut], Laleh Haghverdi [ctb], Maren Büttner [ctb], Fabian Theis [ctb], Carsten Marr [ctb], Florian Büttner [ctb]

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NEWS

# Install 'destiny' in R:
install.packages('destiny', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Bug tracker:https://github.com/theislab/destiny/issues

Uses libs:
  • c++– GNU Standard C++ Library v3
Datasets:
  • guo - Guo at al. mouse embryonic stem cell qPCR data
  • guo_norm - Guo at al. mouse embryonic stem cell qPCR data

On BioConductor:destiny-3.19.0(bioc 3.20)destiny-3.18.0(bioc 3.19)

bioconductor-package

50 exports 3.31 score 109 dependencies 18 mentions

Last updated 2 months agofrom:3aca8342cd

Exports:as.data.frameas.ExpressionSetas.matrixbranch_dividecolorlegendcube_helixdatasetdataset<-DiffusionMapdistancedistance<-dm_predictDPTeig_decompeigenvalueseigenvalues<-eigenvectorseigenvectors<-featureNamesfeatureNames<-find_dm_kfind_knnfind_sigmasfind_tipsfortify.DiffusionMapfortify.DPTgene_relevancel_whichncolnrowoptimal_sigmaplotplot_differential_mapplot_gene_relevanceplot_gene_relevance_rankplot.DiffusionMapplot.DPTprintprojection_distrandom_rootread.ExpressionSetscale_color_cube_helixscale_colour_cube_helixscale_fill_cube_helixshowsigmasSigmassigmas<-tipsupdateObject

Dependencies:abindaskpassbackportsBiobaseBiocGenericsbootbroomcarcarDataclassclicolorspacecowplotcpp11crayoncurldata.tableDelayedArrayDEoptimRDerivdoBydplyre1071fansifarvergenericsGenomeInfoDbGenomeInfoDbDataGenomicRangesggplot.multistatsggplot2ggthemesgluegtablehexbinhttrIRangesirlbaisobandjsonliteknn.covertreelabelinglaekenlatticelifecyclelme4lmtestmagrittrMASSMatrixMatrixGenericsMatrixModelsmatrixStatsmgcvmicrobenchmarkmimeminqamodelrmunsellnlmenloptrnnetnumDerivopensslpbkrtestpcaMethodspillarpkgconfigproxypurrrquantregR6rangerRColorBrewerRcppRcppEigenRcppHNSWrlangrobustbaseRSpectraS4ArraysS4Vectorsscalesscatterplot3dSingleCellExperimentsmootherspSparseArraySparseMstringistringrSummarizedExperimentsurvivalsystibbletidyrtidyselectTTRUCSC.utilsutf8vcdvctrsVIMviridisLitewithrxtsXVectorzlibbioczoo

destiny 2.0 brought the Diffusion Pseudo Time (DPT) class

Rendered fromDPT.Rmdusingknitr::rmarkdownon Jul 01 2024.

Last update: 2022-01-29
Started: 2022-01-29

destiny main vignette: Start here!

Rendered fromDiffusion-Maps.Rmdusingknitr::rmarkdownon Jul 01 2024.

Last update: 2022-01-29
Started: 2022-01-29

detecting relevant genes with destiny 3

Rendered fromGene-Relevance.Rmdusingknitr::rmarkdownon Jul 01 2024.

Last update: 2022-01-29
Started: 2022-01-29

Reproduce the Diffusion Map vignette with the supplied data()

Rendered fromDiffusion-Map-recap.Rmdusingknitr::rmarkdownon Jul 01 2024.

Last update: 2022-01-29
Started: 2022-01-29

The effects of a global vs. local kernel

Rendered fromGlobal-Sigma.Rmdusingknitr::rmarkdownon Jul 01 2024.

Last update: 2022-01-29
Started: 2022-01-29

tidyverse and ggplot integration with destiny

Rendered fromtidyverse.Rmdusingknitr::rmarkdownon Jul 01 2024.

Last update: 2022-01-29
Started: 2022-01-29

Readme and manuals

Help Manual

Help pageTopics
Coercion methodsas.data.frame,DiffusionMap-method as.data.frame,DPT-method as.data.frame.DiffusionMap as.data.frame.DPT as.matrix,DPT-method as.matrix.DPT Coercion methods fortify.DiffusionMap fortify.DPT
Color legendcolorlegend
Sequential color palette using the cube helix systemcube_helix scale_color_cube_helix scale_colour_cube_helix scale_fill_cube_helix
Create and plot diffusion mapsdestiny
destiny genericsdataset dataset<- destiny generics distance distance<- eigenvalues eigenvalues<- eigenvectors eigenvectors<- optimal_sigma sigmas sigmas<-
DiffusionMap accession methodsdataset,DiffusionMap-method dataset<-,DiffusionMap-method DiffusionMap accession methods distance,DiffusionMap-method distance<-,DiffusionMap-method eigenvalues,DiffusionMap-method eigenvalues<-,DiffusionMap-method eigenvectors,DiffusionMap-method eigenvectors<-,DiffusionMap-method optimal_sigma,DiffusionMap-method sigmas,DiffusionMap-method sigmas<-,DiffusionMap-method
DiffusionMap methodsDiffusionMap methods print,DiffusionMap-method print.DiffusionMap show,DiffusionMap-method show.DiffusionMap
Create a diffusion map of cellsDiffusionMap DiffusionMap-class
Predict new data points using an existing DiffusionMap. The resulting matrix can be used in the plot method for the DiffusionMapdm_predict
DPT Matrix methodsdim,DPT-method dim.DPT DPT matrix methods ncol,DPT-method ncol.DPT nrow,DPT-method nrow.DPT [,DPT,index,index,logicalOrMissing-method [,DPT,index,missing,logicalOrMissing-method [,DPT,missing,index,logicalOrMissing-method [,DPT,missing,missing,logicalOrMissing-method [.DPT [[,DPT,index,index-method
DPT methodsbranch_divide dataset,DPT-method dataset.DPT dataset<-,DPT-method DPT methods tips
Diffusion Pseudo TimeDPT DPT-class
Fast eigen decomposition using 'eigs'eig_decomp
Convert object to ExpressionSet or read it from a fileas.ExpressionSet as.ExpressionSet,data.frame-method ExpressionSet helper methods read.ExpressionSet
Extraction methods$,DiffusionMap-method $,DPT-method $.DiffusionMap $.DPT Extraction methods names,DiffusionMap-method names,DPT-method names.DiffusionMap names.DPT [[,DiffusionMap,character,missing-method [[,DPT,character,missing-method [[.DiffusionMap [[.DPT
Find a suitable kfind_dm_k
kNN searchfind_knn
Calculate the average dimensionality for m different gaussian kernel widths (sigma).find_sigmas
Find tips in a DiffusionMap objectfind_tips
Gene Relevance methodsdataset,GeneRelevance-method dataset.GeneRelevance dataset<-,GeneRelevance-method distance,GeneRelevance-method distance<-,GeneRelevance-method featureNames,GeneRelevance-method featureNames.GeneRelevance featureNames<-,GeneRelevance,characterOrFactor-method Gene Relevance methods print,GeneRelevance-method show,GeneRelevance-method
Gene relevances for entire data setGeneRelevance-class gene_relevance gene_relevance,DiffusionMap,missing-method gene_relevance,matrix,dMatrixOrMatrix-method
Guo at al. mouse embryonic stem cell qPCR datadata:guo data:guo_norm guo guo_norm
Logical whichl_which
Plot gene relevance or differential mapGene Relevance plotting plot,GeneRelevance,character-method plot,GeneRelevance,missing-method plot,GeneRelevance,numeric-method plot_differential_map plot_differential_map,DiffusionMap,missing-method plot_differential_map,GeneRelevance,missing-method plot_differential_map,matrix,matrix-method plot_gene_relevance plot_gene_relevance,DiffusionMap,missing-method plot_gene_relevance,GeneRelevance,missing-method plot_gene_relevance,matrix,matrix-method plot_gene_relevance_rank plot_gene_relevance_rank,DiffusionMap,missing-method plot_gene_relevance_rank,GeneRelevance,missing-method plot_gene_relevance_rank,matrix,matrix-method
3D or 2D plot of diffusion mapplot,DiffusionMap,missing-method plot,DiffusionMap,numeric-method plot.DiffusionMap
Plot DPTplot,DPT,missing-method plot,DPT,numeric-method plot.DPT
Plot Sigmas objectplot,Sigmas,missing-method plot.Sigmas
Projection distanceprojection_dist
Find a random root cell indexrandom_root
Sigmas Objectoptimal_sigma,Sigmas-method print,Sigmas-method show,Sigmas-method Sigmas Sigmas-class Sigmas-methods
Update old destiny objects to a newer version.updateObject methods updateObject,DiffusionMap-method updateObject,GeneRelevance-method updateObject,Sigmas-method updateObject.DiffusionMap updateObject.GeneRelevance updateObject.Sigmas