Package: decompTumor2Sig 2.99.0
decompTumor2Sig: Decomposition of individual tumors into mutational signatures by signature refitting
Uses quadratic programming for signature refitting, i.e., to decompose the mutation catalog from an individual tumor sample into a set of given mutational signatures (either Alexandrov-model signatures or Shiraishi-model signatures), computing weights that reflect the contributions of the signatures to the mutation load of the tumor.
Authors:
decompTumor2Sig_2.99.0.tar.gz
decompTumor2Sig_2.99.0.zip(r-4.7-any)decompTumor2Sig_2.99.0.zip(r-4.6-any)decompTumor2Sig_2.99.0.zip(r-4.5-any)
decompTumor2Sig_2.99.0.tar.gz(r-4.7-any)decompTumor2Sig_2.99.0.tar.gz(r-4.6-any)
decompTumor2Sig_2.99.0.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
DESCRIPTION |NEWS
card.svg |card.png
decompTumor2Sig/json (API)
| # Install 'decompTumor2Sig' in R: |
| install.packages('decompTumor2Sig', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org')) |
Bug tracker:https://github.com/rmpiro/decomptumor2sig/issues
On BioConductor:decompTumor2Sig-2.99.0(bioc 3.24)decompTumor2Sig-2.28.1(bioc 3.23)
softwaresnpsequencingdnaseqgenomicvariationsomaticmutationbiomedicalinformaticsgeneticsbiologicalquestionstatisticalmethod
Last updated from:2ef41d46f6. Checks:4 NOTE, 4 OK, 2 FAIL. Indexed: yes.
| Target | Result | Time | Files | Syslog |
|---|---|---|---|---|
| bioc-checks | NOTE | 286 | ||
| linux-devel | OK | 681 | ||
| source / vignettes | OK | 471 | ||
| linux-release | OK | 535 | ||
| macos-release | FAIL | 3864 | ||
| macos-oldrel | FAIL | 3769 | ||
| windows-devel | NOTE | 447 | ||
| windows-release | NOTE | 457 | ||
| windows-oldrel | NOTE | 440 | ||
| wasm-release | OK | 205 |
Exports:adjustSignaturesForRegionSetcomposeGenomesFromExposurescomputeExplainedVarianceconvertAlexandrov2ShiraishiconvertGenomesFromVRangesdecomposeTumorGenomesdetermineSignatureDistancesdowngradeShiraishiSignaturesevaluateDecompositionQualitygetGenomesFromMutFeatDatagetSignaturesFromEstParamisAlexandrovSetisExposureSetisShiraishiSetisSignatureSetmapSignatureSetsplotDecomposedContributionplotExplainedVarianceplotMutationDistributionreadAlexandrovSignaturesreadGenomesFromMPFreadGenomesFromVCFreadShiraishiSignaturessameSignatureFormat
Dependencies:abindAnnotationDbiaskpassBHBiobaseBiocBaseUtilsBiocGenericsBiocIOBiocParallelBiostringsbitbit64bitopsblobBSgenomeBSgenome.Hsapiens.UCSC.hg38cachemcellrangercigarilloclicodetoolscpp11crayoncurldata.tableDBIDelayedArrayfarverfastmapformatRfutile.loggerfutile.optionsgenericsGenomeInfoDbGenomicAlignmentsGenomicFeaturesGenomicRangesggplot2ggseqlogogluegridExtragtablehmshttrIRangesisobandjsonliteKEGGRESTlabelinglambda.rlatticelifecyclemagrittrMatrixMatrixGenericsmatrixStatsmemoisemimeopensslpillarpkgconfigplyrpngprettyunitsprogressquadprogR6RColorBrewerRcppRCurlreadxlrematchrestfulrRhtslibrjsonrlangRsamtoolsRSQLitertracklayerS4ArraysS4VectorsS7scalesSeqinfosnowSparseArraySummarizedExperimentsystibbleTxDb.Hsapiens.UCSC.hg38.knownGeneUCSC.utilsutf8VariantAnnotationvctrsviridisLitewithrXMLXVectoryaml
