Package: TREG 1.17.0

Louise Huuki-Myers

TREG: Tools for finding Total RNA Expression Genes in single nucleus RNA-seq data

RNA abundance and cell size parameters could improve RNA-seq deconvolution algorithms to more accurately estimate cell type proportions given the different cell type transcription activity levels. A Total RNA Expression Gene (TREG) can facilitate estimating total RNA content using single molecule fluorescent in situ hybridization (smFISH). We developed a data-driven approach using a measure of expression invariance to find candidate TREGs in postmortem human brain single nucleus RNA-seq. This R package implements the method for identifying candidate TREGs from snRNA-seq data.

Authors:Louise Huuki-Myers [aut, cre], Leonardo Collado-Torres [ctb]

TREG_1.17.0.tar.gz
TREG_1.17.0.zip(r-4.7)TREG_1.17.0.zip(r-4.6)TREG_1.17.0.zip(r-4.5)
TREG_1.17.0.tgz(r-4.6-any)TREG_1.17.0.tgz(r-4.5-any)
TREG_1.17.0.tar.gz(r-4.7-any)TREG_1.17.0.tar.gz(r-4.6-any)
TREG_1.17.0.tgz(r-4.6-emscripten)
manual.pdf |manual.html
card.svg |card.png
TREG/json (API)
NEWS

# Install 'TREG' in R:
install.packages('TREG', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/lieberinstitute/treg/issues

Pkgdown/docs site:https://research.libd.org

Datasets:

On BioConductor:TREG-1.17.0(bioc 3.24)TREG-1.16.0(bioc 3.23)

softwaresinglecellrnaseqgeneexpressiontranscriptomicstranscriptionsequencingbioconductordeconvolutionrnascopescrna-seqsmfishsnrna-seqtreg

5.48 score 5 stars 5 scripts 324 downloads 6 exports 27 dependencies

Last updated from:930d109d68. Checks:1 NOTE, 9 OK. Indexed: yes.

TargetResultTimeFilesSyslog
bioc-checksNOTE172
linux-devel-x86_64OK269
source / vignettesOK282
linux-release-x86_64OK272
macos-release-arm64OK221
macos-oldrel-arm64OK164
windows-develOK161
windows-releaseOK175
windows-oldrelOK188
wasm-releaseOK144

Exports:filter_prop_zeroget_prop_zerorank_cellsrank_grouprank_invariancerank_invariance_express

Dependencies:abindBiobaseBiocGenericsBiocManagercliDelayedArraygenericsGenomicRangesglueIRangeslatticelifecyclemagrittrMatrixMatrixGenericsmatrixStatspurrrrafalibRColorBrewerrlangS4ArraysS4VectorsSeqinfoSparseArraySummarizedExperimentvctrsXVector

How to find Total RNA Expression Genes (TREGs)

Rendered fromfinding_Total_RNA_Expression_Genes.Rmdusingknitr::rmarkdownon Jun 09 2026.

Last update: 2023-06-16
Started: 2022-03-24