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  "Package": "TREG",
  "Title": "Tools for finding Total RNA Expression Genes in single nucleus\nRNA-seq data",
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  "Date": "2023-06-16",
  "Authors@R": "c(person(given = \"Louise\",\nfamily = \"Huuki-Myers\",\nrole = c(\"aut\", \"cre\"),\nemail = \"lahuuki@gmail.com\",\ncomment = c(ORCID = \"0000-0001-5148-3602\")),\nperson(\"Leonardo\", \"Collado-Torres\", role = c(\"ctb\"),\nemail = \"lcolladotor@gmail.com\", comment = c(ORCID = \"0000-0003-2140-308X\"))\n)",
  "Description": "RNA abundance and cell size parameters could improve\nRNA-seq deconvolution algorithms to more accurately estimate\ncell type proportions given the different cell type\ntranscription activity levels. A Total RNA Expression Gene\n(TREG) can facilitate estimating total RNA content using single\nmolecule fluorescent in situ hybridization (smFISH). We\ndeveloped a data-driven approach using a measure of expression\ninvariance to find candidate TREGs in postmortem human brain\nsingle nucleus RNA-seq. This R package implements the method\nfor identifying candidate TREGs from snRNA-seq data.",
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  "URL": "https://github.com/LieberInstitute/TREG,\nhttp://research.libd.org/TREG/",
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  "Date/Publication": "2026-04-28 12:57:58 UTC",
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