Package: NPARC 1.19.0

Nils Kurzawa

NPARC: Non-parametric analysis of response curves for thermal proteome profiling experiments

Perform non-parametric analysis of response curves as described by Childs, Bach, Franken et al. (2019): Non-parametric analysis of thermal proteome profiles reveals novel drug-binding proteins.

Authors:Dorothee Childs, Nils Kurzawa

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NPARC.pdf |NPARC.html✨
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NEWS

# Install 'NPARC' in R:

install.packages('NPARC', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))

Datasets:

stauro_TPP_data_tidy - TPP dataset of staurosporine treated cells.

On BioConductor:NPARC-1.19.0(bioc 3.21)NPARC-1.18.0(bioc 3.20)

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

software proteomics

5.36 score 38 scripts 212 downloads 6 mentions 5 exports 32 dependencies

Last updated 2 months agofrom:6cd65a155d. Checks:OK: 7. Indexed: yes.

Target	Result	Date
Doc / Vignettes	OK	Dec 22 2024
R-4.5-win	OK	Dec 22 2024
R-4.5-linux	OK	Dec 22 2024
R-4.4-win	OK	Dec 22 2024
R-4.4-mac	OK	Dec 22 2024
R-4.3-win	OK	Dec 22 2024
R-4.3-mac	OK	Dec 22 2024

Exports:fitSingleSigmoid getParams NPARCfit NPARCtest runNPARC

Dependencies:backports BH BiocParallel broom cli codetools cpp11 dplyr fansi formatR futile.logger futile.options generics glue lambda.r lifecycle magrittr MASS pillar pkgconfig purrr R6 rlang snow stringi stringr tibble tidyr tidyselect utf8 vctrs withr

Analysing thermal proteome profiling data with the NPARC package

Dorothee Childs, Nils Kurzawa

Rendered fromNPARC.Rmdusingknitr::rmarkdownon Dec 22 2024.

Last update: 2019-12-24
Started: 2019-12-24

Citation

Development and contributors

Readme and manuals

Help Manual

Help page	Topics
Fit sigmoid model	fitSingleSigmoid
Control parameters for model fitting	getParams
'NPARC' package	NPARC-package NPARC
Fit null and alternative models for Non-parametric analysis of response curves	NPARCfit
Perform F-test	NPARCtest
Non-parametric analysis of response curves	runNPARC
TPP dataset of staurosporine treated cells.	stauro_TPP_data_tidy