Package: MesKit 1.17.0

Mengni Liu

MesKit: A tool kit for dissecting cancer evolution from multi-region derived tumor biopsies via somatic alterations

MesKit provides commonly used analysis and visualization modules based on mutational data generated by multi-region sequencing (MRS). This package allows to depict mutational profiles, measure heterogeneity within or between tumors from the same patient, track evolutionary dynamics, as well as characterize mutational patterns on different levels. Shiny application was also developed for a need of GUI-based analysis. As a handy tool, MesKit can facilitate the interpretation of tumor heterogeneity and the understanding of evolutionary relationship between regions in MRS study.

Authors:Mengni Liu [aut, cre], Jianyu Chen [aut, ctb], Xin Wang [aut, ctb]

MesKit_1.17.0.tar.gz
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MesKit.pdf |MesKit.html
MesKit/json (API)
NEWS

# Install 'MesKit' in R:
install.packages('MesKit', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

On BioConductor:MesKit-1.17.0(bioc 3.21)MesKit-1.16.0(bioc 3.20)

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

4.73 score 1 packages 18 scripts 168 downloads 1 mentions 39 exports 92 dependencies

Last updated 2 months agofrom:471c27c7a0. Checks:OK: 1 WARNING: 6. Indexed: yes.

TargetResultDate
Doc / VignettesOKDec 14 2024
R-4.5-winWARNINGDec 14 2024
R-4.5-linuxWARNINGDec 14 2024
R-4.4-winWARNINGDec 14 2024
R-4.4-macWARNINGDec 14 2024
R-4.3-winWARNINGDec 14 2024
R-4.3-macWARNINGDec 14 2024

Exports:calFstcalJSIcalNeiDistccfAUCclassifyMutcna2genecompareCCFcompareTreefitSignaturesgetBinaryMatrixgetBootstrapValuegetBranchTypegetCCFMatrixgetMafDatagetMafPatientgetMafRefgetMutBranchesgetNonSyn_vcgetPhyloTreegetPhyloTreePatientgetPhyloTreeRefgetPhyloTreeTsbLabelgetSampleInfogetTreegetTreeMethodmathScoremutClustermutHeatmapmutTrunkBranchplotCNAplotMutProfileplotMutSigProfileplotPhyloTreereadMafreadSegmentrunMesKitsubMaftestNeutraltriMatrix

Dependencies:AnnotationDbiapeaskpassBiobaseBiocGenericsBiostringsbitbit64blobcachemcirclizecliclueclustercodetoolscolorspaceComplexHeatmapcowplotcpp11crayoncurldata.tableDBIdigestdoParalleldplyrfansifarverfastmapfastmatchforeachgenericsGenomeInfoDbGenomeInfoDbDataGetoptLongggplot2ggrepelggridgesGlobalOptionsgluegtablehttrigraphIRangesisobanditeratorsjsonliteKEGGRESTlabelinglatticelifecyclemagrittrMASSMatrixmatrixStatsmclustmemoisemgcvmimemunsellnlmeopensslphangornpillarpkgconfigplogrpngpracmapurrrquadprogR6RColorBrewerRcpprjsonrlangRSQLiteS4VectorsscalesshapestringistringrsystibbletidyrtidyselectUCSC.utilsutf8vctrsviridisLitewithrXVectorzlibbioc

MesKit: Analyze and Visualize Multi-region Whole-exome Sequencing Data

Rendered fromMesKit.Rmdusingknitr::rmarkdownon Dec 14 2024.

Last update: 2021-05-07
Started: 2019-12-02

Readme and manuals

Help Manual

Help pageTopics
calFstcalFst
compareJSIcalJSI
calNeiDistcalNeiDist
ccfAUCccfAUC
classifyMutclassifyMut
cna2genecna2gene
compareCCFcompareCCF
compareTreecompareTree
fitSignaturesfitSignatures
getBinaryMatrixgetBinaryMatrix getBinaryMatrix,phyloTree-method
getBootstrapValuegetBootstrapValue getBootstrapValue,phyloTree-method
getBranchTypegetBranchType getBranchType,phyloTree-method
getCCFMatrixgetCCFMatrix getCCFMatrix,phyloTree-method
getMafDatagetMafData getMafData,Maf-method
getMafPatientgetMafPatient getMafPatient,Maf-method
getMafRefgetMafRef getMafRef,Maf-method
getMutBranchesgetMutBranches getMutBranches,phyloTree-method
getNonSyn_vcgetNonSyn_vc getNonSyn_vc,Maf-method
getPhyloTreegetPhyloTree
getPhyloTreePatientgetPhyloTreePatient getPhyloTreePatient,phyloTree-method
getPhyloTreeRefgetPhyloTreeRef getPhyloTreeRef,phyloTree-method getPhyloTreeTsbLabel,phyloTree-method
getPhyloTreeRefgetPhyloTreeTsbLabel
getSampleInfogetSampleInfo getSampleInfo,Maf-method
getTreegetTree getTree,phyloTree-method
getTreeMethodgetTreeMethod getTreeMethod,phyloTree-method
Maf classMaf Maf-class
MafList classMafList MafList-class
mathScoremathScore
mutClustermutCluster
mutHeatmapmutHeatmap
mutTrunkBranchmutTrunkBranch
phyloTree classphyloTree phyloTree-class
phyloTreeList classphyloTreeList-class
plotCNAplotCNA
plotMutProfileplotMutProfile
plotMutSigProfileplotMutSigProfile
plotPhyloTreeplotPhyloTree
readMafreadMaf
readSegmentreadSegment
Run the default MesKit app for analysis locallyrunMesKit
Subset Maf objectsubMaf
testNeutraltestNeutral
triMatrixtriMatrix