Package: DriverNet 1.45.0
Jiarui Ding
DriverNet: Drivernet: uncovering somatic driver mutations modulating transcriptional networks in cancer
DriverNet is a package to predict functional important driver genes in cancer by integrating genome data (mutation and copy number variation data) and transcriptome data (gene expression data). The different kinds of data are combined by an influence graph, which is a gene-gene interaction network deduced from pathway data. A greedy algorithm is used to find the possible driver genes, which may mutated in a larger number of patients and these mutations will push the gene expression values of the connected genes to some extreme values.
Authors:
DriverNet_1.45.0.tar.gz
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DriverNet_1.45.0.tgz(r-4.4-any)DriverNet_1.45.0.tgz(r-4.3-any)
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DriverNet.pdf |DriverNet.html✨
DriverNet/json (API)
| # Install 'DriverNet' in R: |
| install.packages('DriverNet', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org')) |
- sampleDriversList - Sample DriverNet result
- sampleGeneNames - Sample gene names
- sampleInfluenceGraph - Sample influence graph
- samplePatientExpressionMatrix - Sample patient expression matrix
- samplePatientMutationMatrix - Sample patient mutation matrix
- samplePatientOutlierMatrix - Sample patient outlier matrix
- sampleRandomDriversResult - Sample Result from computeRandomizedResult
On BioConductor:DriverNet-1.45.0(bioc 3.20)DriverNet-1.44.0(bioc 3.19)
This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.
Last updated 2 months agofrom:6554729674
Exports:actualEventscomputeDriverscomputeRandomizedResultdriversgetPatientOutlierMatrixpreprocessMatricesresultSummarytotalEvents
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