Package: CHETAH 1.23.0

Jurrian de Kanter

CHETAH: Fast and accurate scRNA-seq cell type identification

CHETAH (CHaracterization of cEll Types Aided by Hierarchical classification) is an accurate, selective and fast scRNA-seq classifier. Classification is guided by a reference dataset, preferentially also a scRNA-seq dataset. By hierarchical clustering of the reference data, CHETAH creates a classification tree that enables a step-wise, top-to-bottom classification. Using a novel stopping rule, CHETAH classifies the input cells to the cell types of the references and to "intermediate types": more general classifications that ended in an intermediate node of the tree.

Authors:Jurrian de Kanter [aut, cre], Philip Lijnzaad [aut]

CHETAH_1.23.0.tar.gz
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CHETAH.pdf |CHETAH.html
CHETAH/json (API)
NEWS

# Install 'CHETAH' in R:
install.packages('CHETAH', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Bug tracker:https://github.com/jdekanter/chetah/issues

Datasets:
  • headneck_ref - A SingleCellExperiment with celltypes in the "celltypes" colData. A subset of the Head-Neck data from Puram et al. (2017) Cancer Cell.
  • input_mel - A SingleCellExperiment on which CHEATHclassifier is run using the 'headneck_ref' It holds subset of the Melanoma data, from Tirosh et al. (2016), Science.

On BioConductor:CHETAH-1.21.0(bioc 3.20)CHETAH-1.20.0(bioc 3.19)

classificationrnaseqsinglecellclusteringgeneexpressionimmunooncology

6.45 score 41 stars 69 scripts 196 downloads 9 exports 104 dependencies

Last updated 23 days agofrom:2fa43fea60. Checks:OK: 7. Indexed: yes.

TargetResultDate
Doc / VignettesOKOct 30 2024
R-4.5-winOKOct 30 2024
R-4.5-linuxOKOct 30 2024
R-4.4-winOKOct 30 2024
R-4.4-macOKOct 30 2024
R-4.3-winOKOct 30 2024
R-4.3-macOKOct 30 2024

Exports:CHETAHclassifierCHETAHshinyClassifyClassifyReferenceCorrelateReferencePlotCHETAHPlotTreePlotTSNERenameBelowNode

Dependencies:abindaskpassbase64encBiobaseBiocGenericsbioDistbslibcachemclicolorspacecommonmarkcorrplotcowplotcpp11crayoncrosstalkcurldata.tableDelayedArraydendextenddigestdplyrevaluatefansifarverfastmapfontawesomefsgenericsGenomeInfoDbGenomeInfoDbDataGenomicRangesggplot2gluegridExtragtablehighrhtmltoolshtmlwidgetshttpuvhttrIRangesisobandjquerylibjsonliteKernSmoothknitrlabelinglaterlatticelazyevallifecyclemagrittrMASSMatrixMatrixGenericsmatrixStatsmemoisemgcvmimemunsellnlmeopensslpheatmappillarpkgconfigplotlyplyrpromisespurrrR6rappdirsRColorBrewerRcppreshape2rlangrmarkdownS4ArraysS4VectorssassscalesshinySingleCellExperimentsourcetoolsSparseArraystringistringrSummarizedExperimentsystibbletidyrtidyselecttinytexUCSC.utilsutf8vctrsviridisviridisLitewithrxfunxtableXVectoryamlzlibbioc

Introduction to the CHETAH package

Rendered fromCHETAH_introduction.Rmdusingknitr::rmarkdownon Oct 30 2024.

Last update: 2022-07-08
Started: 2019-02-17