Package: target 1.19.0

Mahmoud Ahmed

target: Predict Combined Function of Transcription Factors

Implement the BETA algorithm for infering direct target genes from DNA-binding and perturbation expression data Wang et al. (2013) <doi:10.1038/nprot.2013.150>. Extend the algorithm to predict the combined function of two DNA-binding elements from comprable binding and expression data.

Authors:Mahmoud Ahmed [aut, cre]

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NEWS

# Install 'target' in R:
install.packages('target', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Bug tracker:https://github.com/mahshaaban/target/issues

Datasets:
  • real_peaks - AR peaks in LNCaP cell line
  • real_transcripts - Differential expression of DHT treated LNCaP cell line
  • sim_peaks - Simulated peaks
  • sim_transcripts - Simulated transcripts The transcripts chromosome 1 of the mm10 mouse genome with randomly singed statistics assigned to each.

On BioConductor:target-1.19.0(bioc 3.20)target-1.18.0(bioc 3.19)

bioconductor-package

10 exports 0.61 score 45 dependencies 6 mentions

Last updated 2 months agofrom:626e503ee0

Exports:associated_peaksdirect_targetsfind_distancemerge_rangesplot_predictionsrank_productscore_peaksscore_regionstarget_apptest_predictions

Dependencies:askpassbase64encBiocGenericsbslibcachemclicommonmarkcrayoncurldigestfastmapfontawesomefsGenomeInfoDbGenomeInfoDbDataGenomicRangesgluehtmltoolshttpuvhttrIRangesjquerylibjsonlitelaterlifecyclemagrittrmatrixStatsmemoisemimeopensslpromisesR6rappdirsRcpprlangS4VectorssassshinysourcetoolssysUCSC.utilswithrxtableXVectorzlibbioc

Using target to predict combined binding

Rendered fromextend-target.Rmdusingknitr::rmarkdownon Jun 30 2024.

Last update: 2019-09-26
Started: 2019-08-28

Using the target package

Rendered fromtarget.Rmdusingknitr::rmarkdownon Jun 30 2024.

Last update: 2019-08-28
Started: 2019-08-28