Package: target 1.21.0
target: Predict Combined Function of Transcription Factors
Implement the BETA algorithm for infering direct target genes from DNA-binding and perturbation expression data Wang et al. (2013) <doi:10.1038/nprot.2013.150>. Extend the algorithm to predict the combined function of two DNA-binding elements from comprable binding and expression data.
Authors:
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target.pdf |target.html✨
target/json (API)
NEWS
# Install 'target' in R: |
install.packages('target', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org')) |
Bug tracker:https://github.com/mahshaaban/target/issues
- real_peaks - AR peaks in LNCaP cell line
- real_transcripts - Differential expression of DHT treated LNCaP cell line
- sim_peaks - Simulated peaks
- sim_transcripts - Simulated transcripts The transcripts chromosome 1 of the mm10 mouse genome with randomly singed statistics assigned to each.
On BioConductor:target-1.21.0(bioc 3.21)target-1.20.0(bioc 3.20)
softwarestatisticalmethodtranscriptionalgorithmchip-seqdna-bindinggene-regulationtranscription-factors
Last updated 23 days agofrom:9383e81b1c. Checks:OK: 1 WARNING: 6. Indexed: yes.
Target | Result | Date |
---|---|---|
Doc / Vignettes | OK | Nov 14 2024 |
R-4.5-win | WARNING | Nov 14 2024 |
R-4.5-linux | WARNING | Nov 14 2024 |
R-4.4-win | WARNING | Nov 14 2024 |
R-4.4-mac | WARNING | Nov 14 2024 |
R-4.3-win | WARNING | Nov 14 2024 |
R-4.3-mac | WARNING | Nov 14 2024 |
Exports:associated_peaksdirect_targetsfind_distancemerge_rangesplot_predictionsrank_productscore_peaksscore_regionstarget_apptest_predictions
Dependencies:askpassbase64encBiocGenericsbslibcachemclicommonmarkcrayoncurldigestfastmapfontawesomefsgenericsGenomeInfoDbGenomeInfoDbDataGenomicRangesgluehtmltoolshttpuvhttrIRangesjquerylibjsonlitelaterlifecyclemagrittrmatrixStatsmemoisemimeopensslpromisesR6rappdirsRcpprlangS4VectorssassshinysourcetoolssysUCSC.utilswithrxtableXVectorzlibbioc
Readme and manuals
Help Manual
Help page | Topics |
---|---|
Predict associated peaks | associated_peaks |
Predict direct targets | direct_targets |
Find the distance between peaks and regions | find_distance |
Merge peaks and regions GRanges | merge_ranges |
Plot the ECDF of ranks by groups | plot_predictions |
Calculate the regions rank products | rank_product |
AR peaks in LNCaP cell line | real_peaks |
Differential expression of DHT treated LNCaP cell line | real_transcripts |
Calculate peak scores | score_peaks |
Calculate region scores | score_regions |
Simulated peaks | sim_peaks |
Simulated transcripts The transcripts chromosome 1 of the mm10 mouse genome with randomly singed statistics assigned to each. | sim_transcripts |
'target': Predict Combined Function of Transcription Factors. | target-package target |
Run the shiny App | target_app |
Test the ECDF ranks of groups are from same distribution | test_predictions |