Package: splineTimeR 1.41.0

Herbert Braselmann

splineTimeR: Time-course differential gene expression data analysis using spline regression models followed by gene association network reconstruction

This package provides functions for differential gene expression analysis of gene expression time-course data. Natural cubic spline regression models are used. Identified genes may further be used for pathway enrichment analysis and/or the reconstruction of time dependent gene regulatory association networks.

Authors:Agata Michna

splineTimeR_1.41.0.tar.gz
splineTimeR_1.41.0.zip(r-4.7)splineTimeR_1.41.0.zip(r-4.6)splineTimeR_1.41.0.zip(r-4.5)
splineTimeR_1.41.0.tgz(r-4.6-any)splineTimeR_1.41.0.tgz(r-4.5-any)
splineTimeR_1.41.0.tar.gz(r-4.7-any)splineTimeR_1.41.0.tar.gz(r-4.6-any)
splineTimeR_1.41.0.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
card.svg |card.png
splineTimeR/json (API)
NEWS

# Install 'splineTimeR' in R:

install.packages('splineTimeR', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))

Datasets:

TCsimData - Simulated time-course gene expression data set

On BioConductor:splineTimeR-1.41.0(bioc 3.24)splineTimeR-1.40.0(bioc 3.23)

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

geneexpression differentialexpression timecourse regression genesetenrichment networkenrichment networkinference graphandnetwork

4.12 score 22 scripts 419 downloads 3 mentions 5 exports 52 dependencies

Last updated from:69a96090b8. Checks:1 ERROR, 7 NOTE, 2 OK. Indexed: yes.

Target	Result	Time
bioc-checks	ERROR	135
linux-devel-x86_64	NOTE	244
source / vignettes	OK	226
linux-release-x86_64	NOTE	287
macos-release-arm64	NOTE	150
macos-oldrel-arm64	NOTE	114
windows-devel	NOTE	545
windows-release	NOTE	219
windows-oldrel	NOTE	507
wasm-release	OK	115

Exports:networkProperties pathEnrich splineDiffExprs splineNetRecon splinePlot

Dependencies:annotate AnnotationDbi askpass Biobase BiocGenerics Biostrings bit bit64 blob cachem cli corpcor cpp11 crayon curl DBI fastmap fdrtool FIs GeneNet generics glue graph GSEABase gtools httr igraph IRanges jsonlite KEGGREST lattice lifecycle limma longitudinal magrittr Matrix memoise mime openssl pkgconfig png R6 rlang RSQLite S4Vectors Seqinfo statmod sys vctrs XML xtable XVector

splineTimeR

Rendered fromsplineTimeR.Rnwusingutils::Sweaveon May 30 2026.

Last update: 2016-10-05
Started: 2016-03-25

Citation

Development and contributors

Readme and manuals

Help Manual

Help page	Topics
Scale-free properties of a network	networkProperties
Pathway enrichment analysis	pathEnrich
Differential expression analysis based on natural cubic spline regression models for time-course data	splineDiffExprs
Network reconstruction based on partial correlation method with shrinkage approach	splineNetRecon
Plot spline regression curves of time-course data	splinePlot
Simulated time-course gene expression data set	TCsimData