Package: scHOT 1.17.0

Shila Ghazanfar

scHOT: single-cell higher order testing

Single cell Higher Order Testing (scHOT) is an R package that facilitates testing changes in higher order structure of gene expression along either a developmental trajectory or across space. scHOT is general and modular in nature, can be run in multiple data contexts such as along a continuous trajectory, between discrete groups, and over spatial orientations; as well as accommodate any higher order measurement such as variability or correlation. scHOT meaningfully adds to first order effect testing, such as differential expression, and provides a framework for interrogating higher order interactions from single cell data.

Authors:Shila Ghazanfar [aut, cre], Yingxin Lin [aut]

scHOT_1.17.0.tar.gz
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scHOT_1.17.0.tgz(r-4.4-any)scHOT_1.17.0.tgz(r-4.3-any)
scHOT_1.17.0.tar.gz(r-4.5-noble)scHOT_1.17.0.tar.gz(r-4.4-noble)
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scHOT.pdf |scHOT.html
scHOT/json (API)

# Install 'scHOT' in R:
install.packages('scHOT', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Datasets:
  • MOB_subset - MOB_subset spatial example data
  • liver - Liver trajectory example data

On BioConductor:scHOT-1.17.0(bioc 3.20)scHOT-1.16.0(bioc 3.19)

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

bioconductor-package

30 exports 0.71 score 73 dependencies

Last updated 2 months agofrom:e762c77628

Exports:params<-plotColouredExpressionplotEgoNetworkplotHigherOrderSequenceplotOrderedExpressionpositionColData<-positionType<-scHOTscHOT_addTestingScaffoldscHOT_buildFromMatrixscHOT_buildFromSCEscHOT_calculateGlobalHigherOrderFunctionscHOT_calculateHigherOrderTestStatisticsscHOT_estimatePvaluesscHOT_output<-scHOT_performPermutationTestscHOT_plotPermutationDistributionsscHOT_setPermutationScaffoldscHOT_setWeightMatrixscHOT_stripOutputspatialWeightMatrixtestingScaffold<-thintrajectoryWeightMatrixweightedPearsonweightedSpearmanweightedVarianceweightedZIKendallweightedZISpearmanweightMatrix<-

Dependencies:abindaskpassBHBiobaseBiocGenericsBiocParallelclicodetoolscolorspacecpp11crayoncurlDelayedArrayfansifarverformatRfutile.loggerfutile.optionsGenomeInfoDbGenomeInfoDbDataGenomicRangesggforceggplot2gluegtablehttrigraphIRangesisobandjsonlitelabelinglambda.rlatticelifecyclemagrittrMASSMatrixMatrixGenericsmatrixStatsmgcvmimemunsellnlmeopensslpillarpkgconfigplyrpolyclipR6RColorBrewerRcppRcppEigenreshaperlangS4ArraysS4VectorsscalesSingleCellExperimentsnowSparseArraySummarizedExperimentsyssystemfontstibbletidyselecttweenrUCSC.utilsutf8vctrsviridisLitewithrXVectorzlibbioc

Getting started: scHOT

Rendered fromscHOT.Rmdusingknitr::knitron Jun 30 2024.

Last update: 2020-03-11
Started: 2020-01-27

Readme and manuals

Help Manual

Help pageTopics
Liver trajectory example dataliver
MOB_subset spatial example dataMOB_subset
Setter functions for scHOT objectsparams<-
plotColouredExpressionplotColouredExpression
plotEgoNetworkplotEgoNetwork
plotHigherOrderSequenceplotHigherOrderSequence
plotOrderedExpressionplotOrderedExpression
Setter functions for scHOT objectspositionColData<-
Setter functions for scHOT objectspositionType<-
scHOTscHOT
scHOT_addTestingScaffoldscHOT_addTestingScaffold
scHOT_buildFromMatrixscHOT_buildFromMatrix
scHOT_buildFromSCEscHOT_buildFromSCE
scHOT_calculateGlobalHigherOrderFunctionscHOT_calculateGlobalHigherOrderFunction
scHOT_calculateHigherOrderTestStatisticsscHOT_calculateHigherOrderTestStatistics
scHOT_estimatePvaluesscHOT_estimatePvalues
Setter functions for scHOT objectsscHOT_output<-
scHOT_performPermutationTestscHOT_performPermutationTest
scHOT_plotPermutationDistributionsscHOT_plotPermutationDistributions
scHOT_setPermutationScaffoldscHOT_setPermutationScaffold
scHOT_setWeightMatrixscHOT_setWeightMatrix
scHOT_stripOutputscHOT_stripOutput
scHOT class.scHOT scHOT-class
spatialWeightMatrixspatialWeightMatrix
Setter functions for scHOT objectstestingScaffold<-
thinthin
trajectoryWeightMatrixtrajectoryWeightMatrix
weightedPearsonweightedPearson
weightedSpearmanweightedSpearman
weightedVarianceweightedVariance
weightedZIKendallweightedZIKendall
weightedZISpearmanweightedZISpearman
Setter functions for scHOT objectsweightMatrix<-