Package: saseR 1.1.0

Alexandre Segers

saseR: Scalable Aberrant Splicing and Expression Retrieval

saseR is a highly performant and fast framework for aberrant expression and splicing analyses. The main functions are: \itemize{ \item \code{\link{BamtoAspliCounts}} - Process BAM files to ASpli counts \item \code{\link{convertASpli}} - Get gene, bin or junction counts from ASpli SummarizedExperiment \item \code{\link{calculateOffsets}} - Create an offsets assays for aberrant expression or splicing analysis \item \code{\link{saseRfindEncodingDim}} - Estimate the optimal number of latent factors to include when estimating the mean expression \item \code{\link{saseRfit}} - Parameter estimation of the negative binomial distribution and compute p-values for aberrant expression and splicing } For information upon how to use these functions, check out our vignette at \url{https://github.com/statOmics/saseR/blob/main/vignettes/Vignette.Rmd} and the saseR paper: Segers, A. et al. (2023). Juggling offsets unlocks RNA-seq tools for fast scalable differential usage, aberrant splicing and expression analyses. bioRxiv. \url{https://doi.org/10.1101/2023.06.29.547014}.

Authors:Alexandre Segers [aut, cre], Jeroen Gilis [ctb], Mattias Van Heetvelde [ctb], Elfride De Baere [ctb], Lieven Clement [ctb]

saseR_1.1.0.tar.gz
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saseR_1.1.0.tgz(r-4.4-any)saseR_1.1.0.tgz(r-4.3-any)
saseR_1.1.0.tar.gz(r-4.5-noble)saseR_1.1.0.tar.gz(r-4.4-noble)
saseR_1.1.0.tgz(r-4.4-emscripten)saseR_1.1.0.tgz(r-4.3-emscripten)
saseR.pdf |saseR.html
saseR/json (API)
NEWS

# Install 'saseR' in R:
install.packages('saseR', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Bug tracker:https://github.com/statomics/saser/issues

Datasets:

On BioConductor:saseR-1.1.0(bioc 3.20)saseR-1.0.0(bioc 3.19)

bioconductor-package

5 exports 1.24 score 183 dependencies

Last updated 2 months agofrom:a1754de138

Exports:BamtoAspliCountscalculateOffsetsconvertASplisaseRfindEncodingDimsaseRfit

Dependencies:abindannotateAnnotationDbiAnnotationFilteraskpassASpliassertthatbackportsbase64encBHBiobaseBiocFileCacheBiocGenericsBiocIOBiocManagerBiocParallelBiocStylebiomaRtBiostringsbiovizBasebitbit64bitopsblobbookdownBSgenomebslibcachemcheckmatecliclustercodetoolscolorspacecpp11crayoncrosstalkcurldata.tableDBIdbplyrDelayedArraydeldirDEoptimRDESeq2DEXSeqdichromatdigestdplyrDTedgeRensembldbevaluatefansifarverfastmapfilelockfontawesomeforeignformatRFormulafsfutile.loggerfutile.optionsgenefiltergeneplottergenericsGenomeInfoDbGenomeInfoDbDataGenomicAlignmentsGenomicFeaturesGenomicRangesggplot2gluegridExtragtableGvizhighrHmischmshtmlTablehtmltoolshtmlwidgetshttpuvhttrhttr2hwriterigraphinterpIRangesisobandjpegjquerylibjsonliteKEGGRESTknitrlabelinglambda.rlaterlatticelatticeExtralazyevallifecyclelimmalocfitmagrittrMASSMatrixMatrixGenericsmatrixStatsmemoisemgcvmimemunsellmvtnormnlmennetopensslpbmcapplypcaPPpillarpkgconfigplogrplyrpngpracmaprecrecprettyunitsprogresspromisesProtGenericsPRROCpurrrR6rappdirsRColorBrewerRcppRcppArmadilloRcppEigenRCurlrestfulrRhtslibrjsonrlangrmarkdownrobustbaserpartrrcovRsamtoolsRSQLiterstudioapirtracklayerS4ArraysS4VectorssassscalessnowSparseArraystatmodstringistringrSummarizedExperimentsurvivalsystibbletidyrtidyselecttinytextxdbmakerUCSC.utilsUpSetRutf8VariantAnnotationvctrsviridisviridisLitewithrxfunXMLxml2xtableXVectoryamlzlibbioc

Main vignette: Aberrant expression and splicing analysis

Rendered fromsaseR-vignette.Rmdusingknitr::rmarkdownon Jun 30 2024.

Last update: 2024-03-25
Started: 2023-10-10