Package: sarks 1.19.0

Dennis Wylie

sarks: Suffix Array Kernel Smoothing for discovery of correlative sequence motifs and multi-motif domains

Suffix Array Kernel Smoothing (see https://academic.oup.com/bioinformatics/article-abstract/35/20/3944/5418797), or SArKS, identifies sequence motifs whose presence correlates with numeric scores (such as differential expression statistics) assigned to the sequences (such as gene promoters). SArKS smooths over sequence similarity, quantified by location within a suffix array based on the full set of input sequences. A second round of smoothing over spatial proximity within sequences reveals multi-motif domains. Discovered motifs can then be merged or extended based on adjacency within MMDs. False positive rates are estimated and controlled by permutation testing.

Authors:Dennis Wylie [aut, cre]

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NEWS

# Install 'sarks' in R:
install.packages('sarks', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/denniscwylie/sarks/issues

Uses libs:
  • openjdk– OpenJDK Java runtime, using Hotspot JIT
Datasets:

On BioConductor:sarks-1.19.0(bioc 3.21)sarks-1.18.0(bioc 3.20)

motifdiscoverygeneregulationgeneexpressiontranscriptomicsrnaseqdifferentialexpressionfeatureextractionopenjdk

4.78 score 3 stars 3 scripts 200 downloads 19 exports 21 dependencies

Last updated 4 months agofrom:8b05f9a241. Checks:3 OK, 5 NOTE. Indexed: yes.

TargetResultLatest binary
Doc / VignettesOKJan 29 2025
R-4.5-winNOTEJan 29 2025
R-4.5-macNOTEJan 29 2025
R-4.5-linuxNOTEJan 29 2025
R-4.4-winNOTEJan 29 2025
R-4.4-macNOTEJan 29 2025
R-4.3-winOKJan 29 2025
R-4.3-macOKJan 29 2025

Exports:blockInfoblockScoresclusterCountsclusterKmersestimateFalsePositiveRateextendKmerskmerCountskmerPeakslocateClusterslocateKmersmergedKmerSubPeakspermutationDistributionpermutationThresholdspruneIntervalsregexCountsregexLocateSarkssarksFilterssourceBlock

Dependencies:askpassbinomBiocGenericsBiostringsclustercrayoncurlgenericsGenomeInfoDbGenomeInfoDbDatahttrIRangesjsonlitemimeopensslR6rJavaS4VectorssysUCSC.utilsXVector

sarks-vignette

Rendered fromsarks-vignette.Rnwusingutils::Sweaveon Jan 29 2025.

Last update: 2022-02-24
Started: 2020-02-13