Package: plasmut 1.5.0
plasmut: Stratifying mutations observed in cell-free DNA and white blood cells as germline, hematopoietic, or somatic
A Bayesian method for quantifying the liklihood that a given plasma mutation arises from clonal hematopoesis or the underlying tumor. It requires sequencing data of the mutation in plasma and white blood cells with the number of distinct and mutant reads in both tissues. We implement a Monte Carlo importance sampling method to assess the likelihood that a mutation arises from the tumor relative to non-tumor origin.
Authors:
plasmut_1.5.0.tar.gz
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plasmut.pdf |plasmut.html✨
plasmut/json (API)
NEWS
# Install 'plasmut' in R: |
install.packages('plasmut', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org')) |
- crcseq - This data is an example dataset to show how to use the package
On BioConductor:plasmut-1.5.0(bioc 3.21)plasmut-1.4.0(bioc 3.20)
This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.
bayesiansomaticmutationgermlinemutationsequencing
Last updated 5 months agofrom:129bd1d102. Checks:8 OK. Indexed: yes.
Target | Result | Latest binary |
---|---|---|
Doc / Vignettes | OK | Feb 28 2025 |
R-4.5-win | OK | Feb 28 2025 |
R-4.5-mac | OK | Feb 28 2025 |
R-4.5-linux | OK | Feb 28 2025 |
R-4.4-win | OK | Feb 28 2025 |
R-4.4-mac | OK | Feb 28 2025 |
R-4.3-win | OK | Feb 28 2025 |
R-4.3-mac | OK | Feb 28 2025 |
Exports:importance_samplermodel_wplasma_somaticwbc_somatic
Dependencies:clidplyrfansigenericsgluelifecyclemagrittrpillarpkgconfigR6rlangtibbletidyselectutf8vctrswithr