Package: pfamAnalyzeR 1.5.0

Kristoffer Vitting-Seerup

pfamAnalyzeR: Identification of domain isotypes in pfam data

Protein domains is one of the most import annoation of proteins we have with the Pfam database/tool being (by far) the most used tool. This R package enables the user to read the pfam prediction from both webserver and stand-alone runs into R. We have recently shown most human protein domains exist as multiple distinct variants termed domain isotypes. Different domain isotypes are used in a cell, tissue, and disease-specific manner. Accordingly, we find that domain isotypes, compared to each other, modulate, or abolish the functionality of a protein domain. This R package enables the identification and classification of such domain isotypes from Pfam data.

Authors:Kristoffer Vitting-Seerup [cre, aut]

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Bug tracker:https://github.com/kvittingseerup/pfamanalyzer/issues

On BioConductor:pfamAnalyzeR-1.5.0(bioc 3.20)pfamAnalyzeR-1.4.0(bioc 3.19)

bioconductor-package

4 exports 0.71 score 29 dependencies 1 dependents

Last updated 2 months agofrom:b38e61b1a7

Exports:analyse_pfam_isotypesaugment_pfampfamAnalyzeRread_pfam

Dependencies:bitbit64clicliprcpp11crayondplyrfansigenericsgluehmslifecyclemagrittrpillarpkgconfigprettyunitsprogressR6readrrlangstringistringrtibbletidyselecttzdbutf8vctrsvroomwithr