Package: oncomix 1.29.0

Daniel Pique

oncomix: Identifying Genes Overexpressed in Subsets of Tumors from Tumor-Normal mRNA Expression Data

This package helps identify mRNAs that are overexpressed in subsets of tumors relative to normal tissue. Ideal inputs would be paired tumor-normal data from the same tissue from many patients (>15 pairs). This unsupervised approach relies on the observation that oncogenes are characteristically overexpressed in only a subset of tumors in the population, and may help identify oncogene candidates purely based on differences in mRNA expression between previously unknown subtypes.

Authors:Daniel Pique, John Greally, Jessica Mar

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NEWS

# Install 'oncomix' in R:
install.packages('oncomix', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Datasets:
  • exprNmlIsof - Human Breast Cancer RNA-sequencing data from TCGA - Adj. Normal Tissue
  • exprTumIsof - Human Breast Cancer RNA-sequencing data from TCGA - Tumor Tissue
  • queryRes - Oncogene Database Mapping Gene Symbol to UCSC ID

On BioConductor:oncomix-1.29.0(bioc 3.21)oncomix-1.28.0(bioc 3.20)

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

geneexpressionsequencing

3.78 score 4 scripts 179 downloads 3 mentions 8 exports 57 dependencies

Last updated 2 months agofrom:34c2f12980. Checks:OK: 1 NOTE: 6. Indexed: yes.

TargetResultDate
Doc / VignettesOKNov 29 2024
R-4.5-winNOTENov 29 2024
R-4.5-linuxNOTENov 29 2024
R-4.4-winNOTENov 29 2024
R-4.4-macNOTENov 29 2024
R-4.3-winNOTENov 29 2024
R-4.3-macNOTENov 29 2024

Exports:mixModelParamsoncoMixBimodaloncoMixIdealoncoMixTraditionalDEplotGeneHistscatterMixPlottoMatrixtopGeneQuants

Dependencies:abindaskpassBiobaseBiocGenericsclicolorspacecrayoncurlDelayedArrayfansifarvergenericsGenomeInfoDbGenomeInfoDbDataGenomicRangesggplot2ggrepelgluegtablehttrIRangesisobandjsonlitelabelinglatticelifecyclemagrittrMASSMatrixMatrixGenericsmatrixStatsmclustmgcvmimemunsellnlmeopensslpillarpkgconfigR6RColorBrewerRcpprlangS4ArraysS4VectorsscalesSparseArraySummarizedExperimentsystibbleUCSC.utilsutf8vctrsviridisLitewithrXVectorzlibbioc

Oncomix Vignette

Rendered fromoncomix.Rmdusingknitr::rmarkdownon Nov 29 2024.

Last update: 2017-10-10
Started: 2017-08-14