Package: oncomix 1.27.0

Daniel Pique

oncomix: Identifying Genes Overexpressed in Subsets of Tumors from Tumor-Normal mRNA Expression Data

This package helps identify mRNAs that are overexpressed in subsets of tumors relative to normal tissue. Ideal inputs would be paired tumor-normal data from the same tissue from many patients (>15 pairs). This unsupervised approach relies on the observation that oncogenes are characteristically overexpressed in only a subset of tumors in the population, and may help identify oncogene candidates purely based on differences in mRNA expression between previously unknown subtypes.

Authors:Daniel Pique, John Greally, Jessica Mar

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NEWS

# Install 'oncomix' in R:
install.packages('oncomix', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Datasets:
  • exprNmlIsof - Human Breast Cancer RNA-sequencing data from TCGA - Adj. Normal Tissue
  • exprTumIsof - Human Breast Cancer RNA-sequencing data from TCGA - Tumor Tissue
  • queryRes - Oncogene Database Mapping Gene Symbol to UCSC ID

On BioConductor:oncomix-1.27.0(bioc 3.20)oncomix-1.26.0(bioc 3.19)

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

bioconductor-package

8 exports 0.82 score 56 dependencies 3 mentions

Last updated 2 months agofrom:8f2ad6eafb

Exports:mixModelParamsoncoMixBimodaloncoMixIdealoncoMixTraditionalDEplotGeneHistscatterMixPlottoMatrixtopGeneQuants

Dependencies:abindaskpassBiobaseBiocGenericsclicolorspacecrayoncurlDelayedArrayfansifarverGenomeInfoDbGenomeInfoDbDataGenomicRangesggplot2ggrepelgluegtablehttrIRangesisobandjsonlitelabelinglatticelifecyclemagrittrMASSMatrixMatrixGenericsmatrixStatsmclustmgcvmimemunsellnlmeopensslpillarpkgconfigR6RColorBrewerRcpprlangS4ArraysS4VectorsscalesSparseArraySummarizedExperimentsystibbleUCSC.utilsutf8vctrsviridisLitewithrXVectorzlibbioc

Oncomix Vignette

Rendered fromoncomix.Rmdusingknitr::rmarkdownon Jun 30 2024.

Last update: 2017-10-10
Started: 2017-08-14