Package: martini 1.27.0

Hector Climente-Gonzalez

martini: GWAS Incorporating Networks

martini deals with the low power inherent to GWAS studies by using prior knowledge represented as a network. SNPs are the vertices of the network, and the edges represent biological relationships between them (genomic adjacency, belonging to the same gene, physical interaction between protein products). The network is scanned using SConES, which looks for groups of SNPs maximally associated with the phenotype, that form a close subnetwork.

Authors:Hector Climente-Gonzalez [aut, cre], Chloe-Agathe Azencott [aut]

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martini.pdf |martini.html✨
martini/json (API)

# Install 'martini' in R:
install.packages('martini', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/hclimente/martini/issues

Uses libs:
  • c++– GNU Standard C++ Library v3
Datasets:

On BioConductor:martini-1.27.0(bioc 3.21)martini-1.26.0(bioc 3.20)

softwaregenomewideassociationsnpgeneticvariabilitygeneticsfeatureextractiongraphandnetworknetworkbioinformaticsgenomicsgwasnetwork-analysissnpssystems-biologycpp

6.16 score 4 stars 30 scripts 250 downloads 16 exports 21 dependencies

Last updated 4 months agofrom:13d35e1080. Checks:1 OK, 8 NOTE, 2 ERROR. Indexed: yes.

TargetResultLatest binary
Doc / VignettesOKFeb 02 2025
R-4.5-win-x86_64NOTEFeb 02 2025
R-4.5-mac-x86_64ERRORFeb 02 2025
R-4.5-mac-aarch64ERRORFeb 02 2025
R-4.5-linux-x86_64NOTEFeb 02 2025
R-4.4-win-x86_64NOTEFeb 02 2025
R-4.4-mac-x86_64NOTEFeb 02 2025
R-4.4-mac-aarch64NOTEFeb 02 2025
R-4.3-win-x86_64NOTEFeb 02 2025
R-4.3-mac-x86_64NOTEFeb 02 2025
R-4.3-mac-aarch64NOTEFeb 02 2025

Exports:get_GI_networkget_GM_networkget_GS_networkldweight_edgesplot_ideogramsconesscones_scones.cvscones.cv_search_conessigmodsigmod_sigmod.cvsigmod.cv_simulate_causal_snpssimulate_phenotype

Dependencies:BiocGenericscachemclicpp11fastmapgenericsglueigraphlatticelifecyclemagrittrMatrixmemoisepkgconfigRcppRcppEigenrlangsnpStatssurvivalvctrszlibbioc

Running SConES

Héctor Climente-González

Rendered fromscones_usage.Rmdusingknitr::rmarkdownon Feb 02 2025.

Last update: 2021-03-02
Started: 2017-07-13

Simulating SConES-based phenotypes

Héctor Climente-González

Rendered fromsimulate_phenotype.Rmdusingknitr::rmarkdownon Feb 02 2025.

Last update: 2021-03-02
Started: 2017-07-13