Package: loci2path 1.27.0

Tianlei Xu

loci2path: Loci2path: regulatory annotation of genomic intervals based on tissue-specific expression QTLs

loci2path performs statistics-rigorous enrichment analysis of eQTLs in genomic regions of interest. Using eQTL collections provided by the Genotype-Tissue Expression (GTEx) project and pathway collections from MSigDB.

Authors:Tianlei Xu

loci2path_1.27.0.tar.gz
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loci2path.pdf |loci2path.html
loci2path/json (API)
NEWS

# Install 'loci2path' in R:
install.packages('loci2path', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Bug tracker:https://github.com/stanleyxu/loci2path/issues

Datasets:
  • biocarta - EQTL geneset enrichment query demo data
  • eset.list - EQTL geneset enrichment query demo data
  • query.gr - EQTL geneset enrichment query demo data

On BioConductor:loci2path-1.27.0(bioc 3.21)loci2path-1.26.0(bioc 3.20)

functionalgenomicsgeneticsgenesetenrichmentsoftwaregeneexpressionsequencingcoveragebiocarta

4.30 score 1 stars 2 scripts 236 downloads 2 mentions 20 exports 43 dependencies

Last updated 2 months agofrom:1995675b02. Checks:OK: 7. Indexed: yes.

TargetResultDate
Doc / VignettesOKDec 05 2024
R-4.5-winOKDec 05 2024
R-4.5-linuxOKDec 05 2024
R-4.4-winOKDec 05 2024
R-4.4-macOKDec 05 2024
R-4.3-winOKDec 05 2024
R-4.3-macOKDec 05 2024

Exports:check.geneidcoveredGenedescriptioneqtlGeneeqtlIdeqtlRangeeqtlSetgeneSetgeneSetListgetHeatmapgetMatgetPathDescriptiongetPvalgetTissueDegreegetWordcloudloci2pathResultnumGenequeryresultTabletissue

Dependencies:askpassBHBiocGenericsBiocParallelclicodetoolscolorspacecpp11curldata.tablefarverformatRfutile.loggerfutile.optionsgenericsGenomeInfoDbGenomeInfoDbDataGenomicRangesgluegtablehttrIRangesjsonlitelabelinglambda.rlifecyclemimemunsellopensslpheatmapR6RColorBrewerRcpprlangS4VectorsscalessnowsysUCSC.utilsviridisLitewordcloudXVectorzlibbioc

Loci2path: regulatory annotation of genomic intervals based on tissue-specific expression QTLs

Rendered fromloci2path-vignette.Rmdusingknitr::rmarkdownon Dec 05 2024.

Last update: 2018-01-22
Started: 2017-08-19

Readme and manuals

Help Manual

Help pageTopics
eQTL geneset enrichment query demo databiocarta
check compatibility of gene identifiers between eQTL set and gene setcheck.geneid
eqtlSet ClasseqtlGene eqtlGene,eqtlSet-method eqtlId eqtlId,eqtlSet-method eqtlRange eqtlRange,eqtlSet-method eqtlSet eqtlSet-class tissue tissue,eqtlSet-method
eQTL geneset enrichment query demo dataeset.list
geneSet Classdescription description,geneSet-method geneSet geneSet-class geneSetList geneSetList,geneSet-method numGene numGene,geneSet-method
Generate heatmap of enrichment matrix from query resultgetHeatmap getHeatmap,loci2pathResult-method
Extract tissue/geneset enrichment matrix from query resultgetMat getMat,loci2pathResult-method
Extract description for enriched pathways from query result and geneSet objectgetPathDescription getPathDescription,loci2pathResult-method
Extract tissue/geneset enrichment p-value distribution from query resultgetPval getPval,loci2pathResult-method
Extract tissue degree from query resultgetTissueDegree getTissueDegree,loci2pathResult-method
Plot word cloud using frequent terms of pathways and genesgetWordcloud getWordcloud,loci2pathResult-method
loci2pathResult ClasscoveredGene coveredGene,loci2pathResult-method loci2pathResult loci2pathResult-class resultTable resultTable,loci2pathResult-method
Query enrichment in geneset through multiple eQTL sets.query query,eqtlSet,geneSet-method query,GenomicRanges,eqtlSet,geneSet-method query,GenomicRanges,list,ANY-method query,GenomicRanges,list,geneSet-method query,list,geneSet-method query,list-method
eQTL geneset enrichment query demo dataquery.gr