Package: epigenomix 1.47.0

Hans-Ulrich Klein

epigenomix: Epigenetic and gene transcription data normalization and integration with mixture models

A package for the integrative analysis of RNA-seq or microarray based gene transcription and histone modification data obtained by ChIP-seq. The package provides methods for data preprocessing and matching as well as methods for fitting bayesian mixture models in order to detect genes with differences in both data types.

Authors:Hans-Ulrich Klein, Martin Schaefer

epigenomix_1.47.0.tar.gz
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epigenomix_1.47.0.tgz(r-4.4-any)epigenomix_1.47.0.tgz(r-4.3-any)
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epigenomix.pdf |epigenomix.html
epigenomix/json (API)

# Install 'epigenomix' in R:
install.packages('epigenomix', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Datasets:
  • eSet - Example gene expression data set.
  • fpkm - Example RNA-seq data set.
  • mappedReads - Mapped reads obtained from a anti-histone ChIP-seq experiment.
  • transToTSS - A data frame with Ensemble transcript IDs and transcriptional start sites.

On BioConductor:epigenomix-1.47.0(bioc 3.21)epigenomix-1.46.0(bioc 3.20)

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

chipseqgeneexpressiondifferentialexpressionclassification

3.30 score 1 scripts 249 downloads 1 mentions 27 exports 97 dependencies

Last updated 2 months agofrom:6b8078f870. Checks:OK: 3 NOTE: 4. Indexed: yes.

TargetResultDate
Doc / VignettesOKDec 29 2024
R-4.5-winNOTENov 29 2024
R-4.5-linuxNOTEDec 29 2024
R-4.4-winNOTENov 29 2024
R-4.4-macNOTEDec 29 2024
R-4.3-winOKNov 29 2024
R-4.3-macOKDec 29 2024

Exports:acceptanceRateas.data.framebayesMixModelcalculateCrossCorrelationchainsChIPseqSetchipValschipVals<-classificationcomponentsconvergencecpmgetAlignmentQualityintegrateDatalistClassificationMethodsmatchProbeToPromotermlMixModelmmDatanormalizenormalizeChIPplotChainsplotClassificationplotComponentsshowsummarizeReadssummaryweights

Dependencies:abindAnnotationDbiaskpassbase64beadarrayBeadDataPackRBHBiobaseBiocGenericsBiocParallelBiostringsbitbit64bitopsblobcachemclicodacodetoolscolorspacecpp11crayoncurlDBIDelayedArrayfansifarverfastmapformatRfutile.loggerfutile.optionsgenericsGenomeInfoDbGenomeInfoDbDataGenomicRangesggplot2gluegtablehexbinhttrilluminaioIRangesisobandjsonliteKEGGRESTlabelinglambda.rlatticelifecyclelimmamagrittrMASSMatrixMatrixGenericsMatrixModelsmatrixStatsmcmcMCMCpackmemoisemgcvmimemunsellnlmeopensslpillarpkgconfigplogrplyrpngquantregR6RColorBrewerRcppreshape2RhtslibrlangRsamtoolsRSQLiteS4ArraysS4VectorsscalessnowSparseArraySparseMstatmodstringistringrSummarizedExperimentsurvivalsystibbleUCSC.utilsutf8vctrsviridisLitewithrXVector

epigenomix package vignette

Rendered fromepigenomix.Rnwusingutils::Sweaveon Dec 29 2024.

Last update: 2017-04-09
Started: 2013-11-01

Readme and manuals

Help Manual

Help pageTopics
Fits a Bayesian mixture model using Markov Chain Monte Carlo (MCMC) methodsbayesMixModel bayesMixModel,numeric-method
Calculate the cross correlation for a given GRanges object.calculateCrossCorrelation calculateCrossCorrelation,GRanges-method
Class '"ChIPseqSet"'ChIPseqSet ChIPseqSet,matrix,GRanges-method ChIPseqSet,matrix,GRangesList-method ChIPseqSet-class chipVals chipVals,ChIPseqSet-method chipVals<- chipVals<-,ChIPseqSet,matrix-method cpm cpm,ChIPseqSet-method
Example gene expression data set.eSet
Example RNA-seq data set.fpkm
Calculation of basic alignments statisticsgetAlignmentQuality getAlignmentQuality,character-method
Calculates a normalized correlation score from ChIP-seq and microarray gene expression data.integrateData integrateData,ExpressionSet,ChIPseqSet,character,character-method integrateData,ExpressionSet,ChIPseqSet,character,missing-method integrateData,ExpressionSetIllumina,ChIPseqSet,character,character-method integrateData,ExpressionSetIllumina,ChIPseqSet,character,missing-method
Mapped reads obtained from a anti-histone ChIP-seq experiment.mappedReads
A function assigning promoter regions to given probe IDs.matchProbeToPromoter matchProbeToPromoter,list,data.frame-method
Class '"MixModel"'as.data.frame,MixModel-method classification classification,MixModel,character-method classification,MixModel,missing-method components components,MixModel-method dim,MixModel-method length,MixModel-method listClassificationMethods listClassificationMethods,MixModel-method MixModel-class mmData mmData,MixModel-method show,MixModel-method summary,MixModel-method summary,MixModelBayes-method weights,MixModel-method
Class '"MixModelBayes"'acceptanceRate acceptanceRate,MixModelBayes-method chains chains,MixModelBayes-method MixModelBayes-class
Class '"MixModelML"'convergence convergence,MixModelML-method MixModelML-class
Class '"MixtureComponent"'MixtureComponent-class show,MixtureComponent-method
Fits a mixture model using the maximum likelihood principle.mlMixModel mlMixModel,numeric-method
Normalization of ChIP-seq and other count datanormalize normalize,ChIPseqSet-method normalize,ExpressionSet-method
Normalization of ChIP-seq count data. (deprecated)normalizeChIP normalizeChIP,ChIPseqSet,character-method
Produces trace plots for a Bayesian mixture modelplotChains plotChains,MixModelBayes-method
Plot classification obtained from a mixture model.plotClassification plotClassification,MixModel-method
Plots the mixture density together with the densities of all single components.plotComponents plotComponents,MixModel-method
Count reads lying within given regions.summarizeReads summarizeReads,GRangesList,GRanges,character-method summarizeReads,GRangesList,GRanges,missing-method summarizeReads,GRangesList,GRangesList,character-method summarizeReads,GRangesList,GRangesList,missing-method
A data frame with Ensemble transcript IDs and transcriptional start sites.transToTSS