Package: cleanUpdTSeq 1.43.0

Jianhong Ou

cleanUpdTSeq: cleanUpdTSeq cleans up artifacts from polyadenylation sites from oligo(dT)-mediated 3' end RNA sequending data

This package implements a Naive Bayes classifier for accurately differentiating true polyadenylation sites (pA sites) from oligo(dT)-mediated 3' end sequencing such as PAS-Seq, PolyA-Seq and RNA-Seq by filtering out false polyadenylation sites, mainly due to oligo(dT)-mediated internal priming during reverse transcription. The classifer is highly accurate and outperforms other heuristic methods.

Authors:Sarah Sheppard, Haibo Liu, Jianhong Ou, Nathan Lawson, Lihua Julie Zhu

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cleanUpdTSeq.pdf |cleanUpdTSeq.html
cleanUpdTSeq/json (API)
NEWS

# Install 'cleanUpdTSeq' in R:
install.packages('cleanUpdTSeq', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Datasets:

On BioConductor:cleanUpdTSeq-1.43.0(bioc 3.20)cleanUpdTSeq-1.42.0(bioc 3.19)

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

bioconductor-package

5 exports 1.69 score 71 dependencies 1 dependents 2 mentions

Last updated 2 months agofrom:189466ad52

Exports:BED6WithSeq2GRangesSeqbuildClassifierbuildFeatureVectorgetContextSequencespredictTestSet

Dependencies:abindade4askpassBHBiobaseBiocGenericsBiocIOBiocParallelBiostringsbitopsBSgenomeBSgenome.Drerio.UCSC.danRer7classclicodetoolscpp11crayoncurlDelayedArraye1071formatRfutile.loggerfutile.optionsGenomeInfoDbGenomeInfoDbDataGenomicAlignmentsGenomicRangesgluehttrIRangesjsonlitelambda.rlatticelifecyclemagrittrMASSMatrixMatrixGenericsmatrixStatsmimenlmeopensslpixmapproxyR6RcppRcppArmadilloRCurlrestfulrRhtslibrjsonrlangRsamtoolsrtracklayerS4ArraysS4VectorssegmentedseqinrsnowspSparseArraystringistringrSummarizedExperimentsysUCSC.utilsvctrsXMLXVectoryamlzlibbioc

The cleanUpdTSeq user's guide

Rendered fromcleanUpdTSeq.Rmdusingknitr::rmarkdownon Jul 03 2024.

Last update: 2021-04-29
Started: 2015-10-02

Readme and manuals

Help Manual

Help pageTopics
Covert (extended) BED6 file to a GRanges objectBED6WithSeq2GRangesSeq
Build a Naive Bayes ClassifierbuildClassifier
build Feature Vector_2buildFeatureVector
NaiveBayes classifierclassifier
This package classifies putative polyadenylation sites.cleanUpdTSeq-package cleanUpdTSeq
Training Datadata.NaiveBayes
Class '"featureVector"'$,featureVector-method $<-,featureVector-method featureVector featureVector-class
Retrieve upstream and downstream sequencesgetContextSequences
Class '"modelInfo"'$,modelInfo-method $<-,modelInfo-method modelInfo modelInfo-class
Class '"naiveBayes"'$,naiveBayes-method $<-,naiveBayes-method naiveBayes naiveBayes-class
Class '"PASclassifier"'$,PASclassifier-method $<-,PASclassifier-method PASclassifier PASclassifier-class
predict authenticity of putative pA sitespredictTestSet