Package: cleanUpdTSeq 1.51.0

Jianhong Ou

cleanUpdTSeq: cleanUpdTSeq cleans up artifacts from polyadenylation sites from oligo(dT)-mediated 3' end RNA sequending data

This package implements a Naive Bayes classifier for accurately differentiating true polyadenylation sites (pA sites) from oligo(dT)-mediated 3' end sequencing such as PAS-Seq, PolyA-Seq and RNA-Seq by filtering out false polyadenylation sites, mainly due to oligo(dT)-mediated internal priming during reverse transcription. The classifer is highly accurate and outperforms other heuristic methods.

Authors:Sarah Sheppard, Haibo Liu, Jianhong Ou, Nathan Lawson, Lihua Julie Zhu

cleanUpdTSeq_1.51.0.tar.gz
cleanUpdTSeq_1.51.0.zip(r-4.7)cleanUpdTSeq_1.51.0.zip(r-4.6)cleanUpdTSeq_1.51.0.zip(r-4.5)
cleanUpdTSeq_1.51.0.tgz(r-4.6-any)cleanUpdTSeq_1.51.0.tgz(r-4.5-any)
cleanUpdTSeq_1.51.0.tar.gz(r-4.7-any)cleanUpdTSeq_1.51.0.tar.gz(r-4.6-any)
cleanUpdTSeq_1.51.0.tgz(r-4.6-emscripten)
manual.pdf |manual.html
card.svg |card.png
cleanUpdTSeq/json (API)
NEWS

# Install 'cleanUpdTSeq' in R:
install.packages('cleanUpdTSeq', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))
Datasets:

On BioConductor:cleanUpdTSeq-1.51.0(bioc 3.24)cleanUpdTSeq-1.50.0(bioc 3.23)

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

sequencing3 end sequencingpolyadenylation siteinternal priming

4.26 score 1 packages 9 scripts 520 downloads 2 mentions 5 exports 71 dependencies

Last updated from:4d5f8756ee. Checks:1 ERROR, 9 OK. Indexed: yes.

TargetResultTimeFilesSyslog
bioc-checksERROR251
linux-devel-x86_64OK436
source / vignettesOK390
linux-release-x86_64OK415
macos-release-arm64OK227
macos-oldrel-arm64OK377
windows-develOK369
windows-releaseOK352
windows-oldrelOK348
wasm-releaseOK197

Exports:BED6WithSeq2GRangesSeqbuildClassifierbuildFeatureVectorgetContextSequencespredictTestSet

Dependencies:abindade4askpassBHBiobaseBiocBaseUtilsBiocGenericsBiocIOBiocParallelBiostringsbitopsBSgenomeBSgenome.Drerio.UCSC.danRer7cigarilloclassclicodetoolscpp11crayoncurlDelayedArraye1071formatRfutile.loggerfutile.optionsgenericsGenomicAlignmentsGenomicRangesgluehttrIRangesjsonlitelambda.rlatticelifecyclemagrittrMASSMatrixMatrixGenericsmatrixStatsmimenlmeopensslpixmapproxyR6RcppRcppArmadilloRCurlrestfulrRhtslibrjsonrlangRsamtoolsrtracklayerS4ArraysS4VectorssegmentedSeqinfoseqinrsnowspSparseArraystringistringrSummarizedExperimentsysvctrsXMLXVectoryaml

The cleanUpdTSeq user's guide

Rendered fromcleanUpdTSeq.Rmdusingknitr::rmarkdownon May 20 2026.

Last update: 2021-04-29
Started: 2015-10-02

Readme and manuals

Help Manual

Help pageTopics
Covert (extended) BED6 file to a GRanges objectBED6WithSeq2GRangesSeq
Build a Naive Bayes ClassifierbuildClassifier
build Feature Vector_2buildFeatureVector
NaiveBayes classifierclassifier
This package classifies putative polyadenylation sites.cleanUpdTSeq-package cleanUpdTSeq
Training Datadata.NaiveBayes
Class '"featureVector"'$,featureVector-method $<-,featureVector-method featureVector featureVector-class
Retrieve upstream and downstream sequencesgetContextSequences
Class '"modelInfo"'$,modelInfo-method $<-,modelInfo-method modelInfo modelInfo-class
Class '"naiveBayes"'$,naiveBayes-method $<-,naiveBayes-method naiveBayes naiveBayes-class
Class '"PASclassifier"'$,PASclassifier-method $<-,PASclassifier-method PASclassifier PASclassifier-class
predict authenticity of putative pA sitespredictTestSet