Package: biosigner 1.41.0

Etienne A. Thevenot

biosigner: Signature discovery from omics data

Feature selection is critical in omics data analysis to extract restricted and meaningful molecular signatures from complex and high-dimension data, and to build robust classifiers. This package implements a new method to assess the relevance of the variables for the prediction performances of the classifier. The approach can be run in parallel with the PLS-DA, Random Forest, and SVM binary classifiers. The signatures and the corresponding 'restricted' models are returned, enabling future predictions on new datasets. A Galaxy implementation of the package is available within the Workflow4metabolomics.org online infrastructure for computational metabolomics.

Authors:Philippe Rinaudo [aut], Etienne A. Thevenot [aut, cre]

biosigner_1.41.0.tar.gz
biosigner_1.41.0.zip(r-4.7)biosigner_1.41.0.zip(r-4.6)biosigner_1.41.0.zip(r-4.5)
biosigner_1.41.0.tgz(r-4.6-any)biosigner_1.41.0.tgz(r-4.5-any)
biosigner_1.41.0.tar.gz(r-4.7-any)biosigner_1.41.0.tar.gz(r-4.6-any)
biosigner_1.41.0.tgz(r-4.6-emscripten)
manual.pdf |manual.html
card.svg |card.png
biosigner/json (API)
NEWS

# Install 'biosigner' in R:
install.packages('biosigner', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))
Datasets:
  • diaplasma - Analysis of plasma from diabetic patients by LC-HRMS
  • SpikePos - Spike-in metabolomics data for apple extracts

On BioConductor:biosigner-1.41.0(bioc 3.24)biosigner-1.40.0(bioc 3.23)

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

classificationfeatureextractiontranscriptomicsproteomicsmetabolomicslipidomicsmassspectrometry

4.30 score 10 scripts 499 downloads 5 mentions 9 exports 94 dependencies

Last updated from:dcefe5c9c0. Checks:1 WARNING, 7 OK, 2 ERROR. Indexed: yes.

TargetResultTimeFilesSyslog
bioc-checksWARNING199
linux-devel-x86_64OK391
source / vignettesOK331
linux-release-x86_64OK394
macos-release-arm64ERROR249
macos-oldrel-arm64ERROR230
windows-develOK483
windows-releaseOK629
windows-oldrelOK439
wasm-releaseOK175

Exports:biosigngetAccuracyMNgetBiosigngetEsetgetMsetgetSignatureLsplotpredictshow

Dependencies:abindaskpassbase64encBiobaseBiocBaseUtilsBiocGenericsbslibcachemcalibrateclassclicpp11crosstalkcurldata.tableDelayedArraydigestdplyre1071evaluatefarverfastmapfontawesomefsgenericsGenomicRangesggplot2ggrepelgluegtablehighrhtmltoolshtmlwidgetshttrIRangesisobandjquerylibjsonliteknitrlabelinglaterlatticelazyevallifecyclelimmamagrittrMASSMatrixMatrixGenericsmatrixStatsmemoisemimeMultiAssayExperimentMultiDataSetopensslotelpillarpkgconfigplotlypromisesproxypurrrqqmanR6randomForestrappdirsRColorBrewerRcpprlangrmarkdownroplsS4ArraysS4VectorsS7sassscalesSeqinfoSparseArraystatmodstringistringrSummarizedExperimentsystibbletidyrtidyselecttinytexutf8vctrsviridisLitewithrxfunXVectoryaml

biosigner: A new method for signature discovery from omics data

Rendered frombiosigner-vignette.Rmdusingknitr::rmarkdownon May 30 2026.

Last update: 2025-06-23
Started: 2016-09-18

Readme and manuals

Help Manual

Help pageTopics
Molecular signature discovery from omics databiosigner-package biosigner
Builds the molecular signature.biosign biosign,data.frame-method biosign,ExpressionSet-method biosign,matrix-method biosign,MultiAssayExperiment-method biosign,MultiDataSet-method biosign,MultiDataSet_method biosign,SummarizedExperiment-method
Class "biosign"biosign-class
Class "biosignMultiDataSet"biosignMultiDataSet-class
Analysis of plasma from diabetic patients by LC-HRMSdiaplasma
Accuracies of the full model and the models restricted to the signaturesgetAccuracyMN getAccuracyMN,biosign-method
Getting the biosigner signature from the SummarizedExperiment objectgetBiosign getBiosign,MultiAssayExperiment-method getBiosign,SummarizedExperiment-method
getEset methodbiosign-method getEset getEset, getEset,biosign-method
getMset methodbiosignMultiDataSet-method getMset getMset, getMset,biosignMultiDataSet-method
Signatures selected by the modelsgetSignatureLs getSignatureLs,biosign-method
Plot method for 'biosign' signature objectsplot,biosign,ANY-method plot,biosign-method plot,biosignMultiDataSet,ANY-method plot,biosignMultiDataSet-method plot.biosign plot.biosignMultiDataSet
Predict method for 'biosign' signature objectspredict,biosign-method predict.biosign
Show method for 'biosign' signature objectsshow,biosign-method show.biosign
Spike-in metabolomics data for apple extracts (from the BioMark package)SpikePos