Package: Xeva 1.23.1

Benjamin Haibe-Kains

Xeva: Analysis of patient-derived xenograft (PDX) data

The Xeva package provides efficient and powerful functions for patient-drived xenograft (PDX) based pharmacogenomic data analysis. This package contains a set of functions to perform analysis of patient-derived xenograft data. This package was developed by the BHKLab, for further information please see our documentation.

Authors:Arvind Mer [aut], Benjamin Haibe-Kains [aut, cre]

Xeva_1.23.1.tar.gz
Xeva_1.23.1.zip(r-4.5)Xeva_1.23.1.zip(r-4.4)Xeva_1.23.1.zip(r-4.3)
Xeva_1.23.1.tgz(r-4.4-any)Xeva_1.23.1.tgz(r-4.3-any)
Xeva_1.23.1.tar.gz(r-4.5-noble)Xeva_1.23.1.tar.gz(r-4.4-noble)
Xeva_1.23.1.tgz(r-4.4-emscripten)Xeva_1.23.1.tgz(r-4.3-emscripten)
Xeva.pdf |Xeva.html
Xeva/json (API)
NEWS

# Install 'Xeva' in R:
install.packages('Xeva', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Bug tracker:https://github.com/bhklab/xeva/issues

Datasets:
  • PDXMI - PDX-MI data
  • brca - PDXE breast cancer dataset
  • repdx - Example PDX dataset

On BioConductor:Xeva-1.23.0(bioc 3.21)Xeva-1.22.0(bioc 3.20)

geneexpressionpharmacogeneticspharmacogenomicssoftwareclassification

6.26 score 9 stars 17 scripts 332 downloads 28 exports 159 dependencies

Last updated 28 days agofrom:54c191f813. Checks:OK: 1 ERROR: 6. Indexed: yes.

TargetResultDate
Doc / VignettesOKNov 28 2024
R-4.5-winERRORDec 04 2024
R-4.5-linuxERRORDec 04 2024
R-4.4-winERRORDec 04 2024
R-4.4-macERRORDec 04 2024
R-4.3-winERRORDec 04 2024
R-4.3-macERRORDec 04 2024

Exports:ABCaddExperimentalDesignangleAUCbatchInfocreateXevaSetdosePlotdownloadXevaSetdrugInformdrugSensitivitySiggetExperimentgetMolecularProfileslmmmodelInfomRECISTplotBatchplotmRECISTplotPDXresponseselectModelIdssensitivitysetResponseslopesubsetXevasummarizeMolecularProfilessummarizeResponseTGIwaterfall

Dependencies:abindaskpassbackportsbase64encBBmiscbenchBHBiobaseBiocBaseUtilsBiocGenericsBiocParallelbitopsbootbslibBumpyMatrixcachemcaToolscelestialcheckmatecirclizecliclueclustercodetoolscolorspacecommonmarkComplexHeatmapcoopCoreGxcowplotcpp11crayoncrosstalkcurldata.tableDelayedArraydigestdoParalleldownloaderdplyrDTevaluatefansifarverfastmapfastmatchfgseafontawesomeforeachformatRfsfutile.loggerfutile.optionsgenericsGenomeInfoDbGenomeInfoDbDataGenomicRangesGetoptLongggplot2GlobalOptionsgluegplotsgtablegtoolshighrhtmltoolshtmlwidgetshttpuvhttrigraphIRangesisobanditeratorsjquerylibjsonliteKernSmoothknitrlabelinglambda.rlaterlatticelazyevallifecyclelimmalsamagicaxismagrittrmapprojmapsmarrayMASSMatrixMatrixGenericsmatrixStatsmemoisemgcvmimeMultiAssayExperimentmunsellNISTunitsnlmeopensslPharmacoGxpianopillarpkgconfigplotrixplyrpngpracmaprofmempromisespurrrR6RANNrappdirsRColorBrewerRcpprelationsreshape2rjsonrlangrmarkdownRmiscS4ArraysS4VectorssassscalessetsshapeshinyshinydashboardshinyjsslamsmsnowSnowballCsourcetoolsSparseArraystatmodstringistringrSummarizedExperimentsystibbletidyrtidyselecttinytexUCSC.utilsutf8vctrsviridisLitevisNetworkwithrxfunxtableXVectoryamlzlibbioc

The Xeva User's Guide

Rendered fromXeva.Rnwusingknitr::knitron Nov 28 2024.

Last update: 2023-04-19
Started: 2019-03-06

Readme and manuals

Help Manual

Help pageTopics
area between curves Computes the area between two time-volume curves.ABC
Add a new experimental designaddExperimentalDesign addExperimentalDesign,XevaSet-method
compute angle Computes the angle between two time-volume curves.angle
area under the curve 'AUC' Returns area under the curveAUC
Get batch informationbatchInfo batchInfo,XevaSet-method
PDXE breast cancer datasetbrca
XevaSet constructorcreateXevaSet
plot dose datadosePlot
Download a XevaSet object or table of available XevaSet objectsdownloadXevaSet
Get drug information Get the drug information slot from a XevaSet object.drugInform drugInform,XevaSet-method
get drug sensitivity valuesdrugSensitivitySig
Get PDX experiment datagetExperiment getExperiment,XevaSet-method
Get molecular profiles from a XevaSet objectgetMolecularProfiles
linear mixed modellmm
modelInfo Generic Generic for modelInfo methodmodelInfo modelInfo,XevaSet-method
Computes the mRECISTmRECIST
PDX-MI dataPDXMI
To plot mRECIST valuesplotmRECIST
Plot batch dataplotBatch plotPDX
Print the batch responseprint.batchResponse
Print the model responseprint.modelResponse
Print the pdx batchprint.pdxBatch
Example PDX datasetrepdx
compute PDX responseresponse
To select model IDs based on drug name and/or tissue type.selectModelIds selectModelIds,XevaSet-method
Get sensitivity for an Xeva objectsensitivity
set PDX responsesetResponse
Computes slopeslope
Subset Xeva object.subsetXeva
Summarize molecular profilessummarizeMolecularProfiles
Summarize Response of PDXssummarizeResponse
tumor growth inhibition (TGI) Computes the tumor growth inhibition (TGI) between two time-volume curvesTGI
waterfall plot Creates waterfall plot for a given drug.waterfall