Package: NanoStringDiff 1.37.0

tingting zhai

NanoStringDiff: Differential Expression Analysis of NanoString nCounter Data

This Package utilizes a generalized linear model(GLM) of the negative binomial family to characterize count data and allows for multi-factor design. NanoStrongDiff incorporate size factors, calculated from positive controls and housekeeping controls, and background level, obtained from negative controls, in the model framework so that all the normalization information provided by NanoString nCounter Analyzer is fully utilized.

Authors:hong wang <[email protected]>, tingting zhai <[email protected]>, chi wang <[email protected]>

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NanoStringDiff.pdf |NanoStringDiff.html
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NEWS

# Install 'NanoStringDiff' in R:
install.packages('NanoStringDiff', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Uses libs:
  • c++– GNU Standard C++ Library v3
Datasets:

On BioConductor:NanoStringDiff-1.35.0(bioc 3.20)NanoStringDiff-1.34.0(bioc 3.19)

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

differentialexpressionnormalization

4.30 score 3 scripts 218 downloads 22 mentions 25 exports 4 dependencies

Last updated 23 days agofrom:ceaa04c058. Checks:OK: 1 WARNING: 8. Indexed: yes.

TargetResultDate
Doc / VignettesOKOct 30 2024
R-4.5-win-x86_64WARNINGOct 30 2024
R-4.5-linux-x86_64WARNINGOct 30 2024
R-4.4-win-x86_64WARNINGOct 30 2024
R-4.4-mac-x86_64WARNINGOct 30 2024
R-4.4-mac-aarch64WARNINGOct 30 2024
R-4.3-win-x86_64WARNINGOct 30 2024
R-4.3-mac-x86_64WARNINGOct 30 2024
R-4.3-mac-aarch64WARNINGOct 30 2024

Exports:compute.baseSigmacreateNanoStringSetcreateNanoStringSetFromCsvest.dispersionestNormalizationFactorsfun5glm.LRTglmfit.fullglmfit.OneGroupglmfit.reducehousekeepingControlhousekeepingControl<-housekeepingFactorhousekeepingFactor<-NanoStringDataNormalizationnegativeControlnegativeControl<-negativeFactornegativeFactor<-PlotsPositiveHousekeepingpositiveControlpositiveControl<-positiveFactorpositiveFactor<-rnegbinom

Dependencies:BiobaseBiocGenericsmatrixStatsRcpp

NanoStringDiff Vignette

Rendered fromNanoStringDiff.Rnwusingutils::Sweaveon Oct 30 2024.

Last update: 2018-01-25
Started: 2015-08-06

Readme and manuals

Help Manual

Help pageTopics
A short title line describing what the package doesNanoStringDiff-package NanoStringDiff
estimate normalization factors,include positive size factors, background noise, housekeeping size factors.estNormalizationFactors estNormalizationFactors,estNormalizationFactors-method
perform gene-wise likelihood ratio test for NanoString Dataglm.LRT glm.LRT,NanoStringSet-method
Acessor functions for the 'housekeepingControl' slot in a NanoStringSet object.housekeepingControl housekeepingControl,NanoStringSet-method housekeepingControl<- housekeepingControl<-,NanoStringSet,matrix-method
Acessor functions for the 'housekeepingFactor' slot in a NanoStringSet object.housekeepingFactor housekeepingFactor,NanoStringSet-method housekeepingFactor<- housekeepingFactor<-,NanoStringSet,numeric-method
A real 'NanoStringSet' object.NanoStringData
Normalize NanoStringDataNanoStringDataNormalization NanoStringDataNormalization,NanoStringDataNormalization-method
NanoStringSet object and constructorscreateNanoStringSet createNanoStringSetFromCsv NanoStringSet NanoStringSet-class
Acessor functions for the 'negativeControl' slot in a NanoStringSet object.negativeControl negativeControl,NanoStringSet-method negativeControl<- negativeControl<-,NanoStringSet,matrix-method
Acessor functions for the 'negativeFactor' slot in a NanoStringSet object.negativeFactor negativeFactor,NanoStringSet-method negativeFactor<- negativeFactor<-,NanoStringSet,numeric-method
Plots of positive controls and housekeeping genesPlotsPositiveHousekeeping PlotsPositiveHousekeeping,PlotsPositiveHousekeeping-method
Acessor functions for the 'positiveControl' slot in a NanoStringSet object.positiveControl positiveControl,NanoStringSet-method positiveControl<- positiveControl<-,NanoStringSet,matrix-method
Acessor functions for the 'positiveFactor' slot in a NanoStringSet object.positiveFactor positiveFactor,NanoStringSet-method positiveFactor<- positiveFactor<-,NanoStringSet,numeric-method