Package: MAGAR 1.21.0

Michael Scherer
MAGAR: MAGAR: R-package to compute methylation Quantitative Trait Loci (methQTL) from DNA methylation and genotyping data
"Methylation-Aware Genotype Association in R" (MAGAR) computes methQTL from DNA methylation and genotyping data from matched samples. MAGAR uses a linear modeling stragety to call CpGs/SNPs that are methQTLs. MAGAR accounts for the local correlation structure of CpGs.
Authors:
MAGAR_1.21.0.tar.gz
MAGAR_1.21.0.zip(r-4.7)MAGAR_1.21.0.zip(r-4.6)MAGAR_1.21.0.zip(r-4.5)
MAGAR_1.21.0.tgz(r-4.6-any)MAGAR_1.21.0.tgz(r-4.5-any)
MAGAR_1.21.0.tar.gz(r-4.7-any)MAGAR_1.21.0.tar.gz(r-4.6-any)
MAGAR_1.21.0.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
card.svg |card.png
MAGAR/json (API)
NEWS
| # Install 'MAGAR' in R: |
| install.packages('MAGAR', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org')) |
Bug tracker:https://github.com/mpiicomputationalepigenetics/magar/issues
On BioConductor:MAGAR-1.21.0(bioc 3.24)MAGAR-1.20.0(bioc 3.23)
regressionepigeneticsdnamethylationsnpgeneticvariabilitymethylationarraymicroarraycpgislandmethylseqsequencingmrnamicroarraypreprocessingcopynumbervariationtwochannelimmunooncologydifferentialmethylationbatcheffectqualitycontroldataimportnetworkclusteringgraphandnetwork
Last updated from:a893c77495. Checks:8 NOTE, 2 OK. Indexed: yes.
| Target | Result | Time | Files | Syslog |
|---|---|---|---|---|
| bioc-checks | NOTE | 384 | ||
| linux-devel-x86_64 | NOTE | 722 | ||
| source / vignettes | OK | 521 | ||
| linux-release-x86_64 | NOTE | 699 | ||
| macos-release-arm64 | NOTE | 539 | ||
| macos-oldrel-arm64 | NOTE | 374 | ||
| windows-devel | NOTE | 939 | ||
| windows-release | NOTE | 679 | ||
| windows-oldrel | NOTE | 981 | ||
| wasm-release | OK | 327 |
Exports:computeCorrelationBlocksdoImportdoMethQTLdoMethQTLChromosomefilterPvalgetAnnogetCorrelationBlocksgetGenogetMethDatagetOverlappingQTLgetOverlapUniversegetPhenogetResultgetResultGWASMapgetSamplesgetSpecificQTLimputeMethjoinMethQTLResultloadMethQTLInputloadMethQTLResultoverlapInputsoverlapQTLsqtlAnnotationEnrichmentqtlBaseSubstitutionEnrichmentqtlDistanceScatterplotqtlGetOptionqtlJSON2optionsqtlManhattanPlotqtlOptions2JSONqtlPlotBaseSubstitutionqtlPlotClusterSizeqtlPlotSNPCpGInteractionqtlSetOptionqtlTFBSMotifEnrichmentqtlUpsetPlotqtlUpSetPlotCorBlocksqtlUpSetPlotTagCpGsqtlVennPlotsaveMethQTLInputsaveMethQTLResult
Dependencies:abindaffyioannotateAnnotationDbiargparseaskpassbase64beanplotBHbigassertrbigparallelrbigstatsrBiobaseBiocBaseUtilsBiocGenericsBiocIObiocmakeBiocManagerBiocParallelBiostringsbitbit64bitopsblobbumphuntercachemcaToolscigarilloclicliprclustercodetoolscowplotcpp11crayoncrlmmcurldata.tableDBIDelayedArrayDelayedMatrixStatsdigestdir.expirydoParalleldoRNGdotCall64dplyrellipsefarverfastmapFDb.InfiniumMethylation.hg19fffieldsfilelockfindpythonflockforeachformatRfutile.loggerfutile.optionsgenefiltergenericsGenomeInfoDbGenomicAlignmentsGenomicFeaturesGenomicRangesGEOqueryggplot2gluegplotsgridExtragtablegtoolsh5mreadHDF5Arrayhmshttrhttr2igraphilluminaioimputeIRangesisobanditeratorsjsonliteKEGGRESTKernSmoothlabelinglambda.rlatticelifecyclelimmalocfitmagrittrmapsMASSMatrixMatrixGenericsmatrixStatsmclustmemoisemethylumimimeminfimulttestmvtnormnlmenor1mixoligoClassesopensslorg.Hs.eg.dbparallellypillarpkgconfigplyrpngpreprocessCoreprettyunitsprogresspspurrrquadprogR.methodsS3R.ooR.utilsR6rappdirsRColorBrewerRcppRcppArmadilloRcppEigenRCurlreadrrentrezreshapereshape2restfulrrhdf5rhdf5filtersRhdf5libRhpcBLASctlRhtslibrjsonrlangrmioRnBeadsRnBeads.hg19RnBeads.hg38rngtoolsRsamtoolsRSpectraRSQLitertracklayerrvestS4ArraysS4VectorsS7scalesscrimeselectrSeqinfosiggenessnowsnpStatsspamSparseArraysparseMatrixStatsstatmodstringistringrSummarizedExperimentsurvivalsystibbletidyrtidyselectTxDb.Hsapiens.UCSC.hg19.knownGenetzdbUCSC.utilsUpSetRutf8vctrsVGAMviridisLitevroomwithrXMLxml2xtableXVectoryaml
Readme and manuals
Help Manual
| Help page | Topics |
|---|---|
| computeCorrelationBlocks | computeCorrelationBlocks |
| doImport | doImport |
| doMethQTL | doMethQTL |
| doMethQTLChromosome | doMethQTLChromosome |
| filterPval | filterPval filterPval,MethQTLResult-method |
| getAnno | getAnno getAnno,methQTL-method getAnno,MethQTLInput-method getAnno,MethQTLResult-method |
| getCorrelationBlocks | getCorrelationBlocks getCorrelationBlocks,MethQTLResult-method |
| getGeno | getGeno getGeno,methQTL-method getGeno,MethQTLInput-method |
| getMethData | getMethData getMethData,methQTL-method getMethData,MethQTLInput-method |
| getOverlappingQTL | getOverlappingQTL |
| getOverlapUniverse | getOverlapUniverse |
| getPheno | getPheno getPheno,methQTL-method getPheno,MethQTLInput-method |
| getResult | getResult getResult,MethQTLResult-method |
| getResultGWASMap | getResultGWASMap getResultGWASMap,MethQTLResult-method |
| getSamples | getSamples getSamples,methQTL-method getSamples,MethQTLInput-method |
| getSpecificQTL | getSpecificQTL |
| imputeMeth | imputeMeth imputeMeth,methQTL-method imputeMeth,MethQTLInput-method |
| joinMethQTLResult | joinMethQTLResult |
| loadMethQTLInput | loadMethQTLInput |
| loadMethQTLResult | loadMethQTLResult |
| MethQTLInput-class | MethQTLInput-class |
| MethQTLResult-class | MethQTLResult-class |
| overlapInputs | overlapInputs |
| overlapQTLs | overlapQTLs |
| options.R | QTL.OPTIONS |
| qtlAnnotationEnrichment | qtlAnnotationEnrichment |
| qtlBaseSubstitutionEnrichment | qtlBaseSubstitutionEnrichment |
| qtlDistanceScatterplot | qtlDistanceScatterplot |
| qtlGetOption Print the value of the global option | qtlGetOption |
| qtlJSON2options | qtlJSON2options |
| qtlManhattanPlot | qtlManhattanPlot |
| qtlOptions2JSON | qtlOptions2JSON |
| qtlPlotBaseSubstitution | qtlPlotBaseSubstitution |
| qtlPlotClusterSize | qtlPlotClusterSize |
| qtlPlotSNPCpGInteraction | qtlPlotSNPCpGInteraction |
| qtlSetOption | qtlSetOption |
| qtlTFBSMotifEnrichment | qtlTFBSMotifEnrichment |
| qtlUpsetPlot | qtlUpsetPlot |
| qtlUpSetPlotCorBlocks | qtlUpSetPlotCorBlocks |
| qtlUpSetPlotTagCpGs | qtlUpSetPlotTagCpGs |
| qtlVennPlot | qtlVennPlot |
| saveMethQTLInput | saveMethQTLInput saveMethQTLInput,methQTL-method saveMethQTLInput,MethQTLInput-method |
| saveMethQTLResult | saveMethQTLResult saveMethQTLResult,methQTL-method saveMethQTLResult,MethQTLResult-method |