Package: DeMAND 1.43.0

Jung Hoon Woo
DeMAND: DeMAND
DEMAND predicts Drug MoA by interrogating a cell context specific regulatory network with a small number (N >= 6) of compound-induced gene expression signatures, to elucidate specific proteins whose interactions in the network is dysregulated by the compound.
Authors:
DeMAND_1.43.0.tar.gz
DeMAND_1.43.0.zip(r-4.7)DeMAND_1.43.0.zip(r-4.6)DeMAND_1.43.0.zip(r-4.5)
DeMAND_1.43.0.tgz(r-4.6-any)DeMAND_1.43.0.tgz(r-4.5-any)
DeMAND_1.43.0.tar.gz(r-4.7-any)DeMAND_1.43.0.tar.gz(r-4.6-any)
DeMAND_1.43.0.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
card.svg |card.png
DeMAND/json (API)
| # Install 'DeMAND' in R: |
| install.packages('DeMAND', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org')) |
- bcellAnno - Annotation for the expression data
- bcellExp - B cell expression data
- bcellNetwork - B cell network
- caseIndex - Case sample index
- controlIndex - Control sample index
On BioConductor:DeMAND-1.43.0(bioc 3.24)DeMAND-1.42.0(bioc 3.23)
This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.
systemsbiologynetworkenrichmentgeneexpressionstatisticalmethodnetwork
Last updated from:d7eee9f2d8. Checks:1 ERROR, 7 NOTE, 2 OK. Indexed: yes.
| Target | Result | Time | Files | Syslog |
|---|---|---|---|---|
| bioc-checks | ERROR | 129 | ||
| linux-devel-x86_64 | NOTE | 149 | ||
| source / vignettes | OK | 147 | ||
| linux-release-x86_64 | NOTE | 114 | ||
| macos-release-arm64 | NOTE | 101 | ||
| macos-oldrel-arm64 | NOTE | 85 | ||
| windows-devel | NOTE | 89 | ||
| windows-release | NOTE | 77 | ||
| windows-oldrel | NOTE | 67 | ||
| wasm-release | OK | 84 |
Exports:demandClassprintDeMANDrunDeMAND
Dependencies:KernSmooth
Readme and manuals
Help Manual
| Help page | Topics |
|---|---|
| Annotation for the expression data | bcellAnno |
| B cell expression data | bcellExp |
| B cell network | bcellNetwork |
| Case sample index | caseIndex |
| Control sample index | controlIndex |
| The DeMAND instance | demand-instance |
| The demand class constructor | demandClass |
| Basic methods for class demand | printDeMAND |
| Run DeMAND algorithm | runDeMAND |