Package: DOSE 3.31.2

Guangchuang Yu

DOSE: Disease Ontology Semantic and Enrichment analysis

This package implements five methods proposed by Resnik, Schlicker, Jiang, Lin and Wang respectively for measuring semantic similarities among DO terms and gene products. Enrichment analyses including hypergeometric model and gene set enrichment analysis are also implemented for discovering disease associations of high-throughput biological data.

Authors:Guangchuang Yu [aut, cre], Li-Gen Wang [ctb], Vladislav Petyuk [ctb], Giovanni Dall'Olio [ctb], Erqiang Hu [ctb]

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NEWS

# Install 'DOSE' in R:
install.packages('DOSE', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Bug tracker:https://github.com/guangchuangyu/dose/issues

Datasets:

On BioConductor:DOSE-3.31.1(bioc 3.20)DOSE-3.30.1(bioc 3.19)

bioconductor-package

30 exports 5.31 score 83 dependencies 58 dependents 138 mentions

Last updated 27 days agofrom:98301d9860

Exports:clusterSimdoseSimdoSimenrichDGNenrichDGNvenrichDOenrichHPOenrichMPOenrichNCGEXTID2NAMEfacet_gridgene2DOgeneIDgeneInCategorygeneSimgseDGNgseDOgseHPOgseMPOgseNCGgsfilterhpoSimmclusterSimmpoSimparse_ratiosetReadableshowsimplotsummarytheme_dose

Dependencies:AnnotationDbiaskpassBHBiobaseBiocGenericsBiocParallelBiostringsbitbit64blobcachemclicodetoolscolorspacecowplotcpp11crayoncurldata.tableDBIdigestfansifarverfastmapfastmatchfgseaformatRfsfutile.loggerfutile.optionsGenomeInfoDbGenomeInfoDbDataggplot2glueGO.dbGOSemSimgtableHDO.dbhttrIRangesisobandjsonliteKEGGRESTlabelinglambda.rlatticelifecyclemagrittrMASSMatrixmemoisemgcvmimemunsellnlmeopensslpillarpkgconfigplogrplyrpngqvalueR6RColorBrewerRcppreshape2rlangRSQLiteS4VectorsscalessnowstringistringrsystibbleUCSC.utilsutf8vctrsviridisLitewithrXVectoryulab.utilszlibbioc

DOSE: Disease Ontology Semantic and Enrichment analysis

Rendered fromDOSE.Rmdusingknitr::rmarkdownon Jun 14 2024.

Last update: 2020-09-09
Started: 2015-06-24

Readme and manuals

Help Manual

Help pageTopics
clusterSimclusterSim
Class "compareClusterResult" This class represents the comparison result of gene clusters by GO categories at specific level or GO enrichment analysis.compareClusterResult-class plot,compareClusterResult-method show,compareClusterResult-method summary,compareClusterResult-method
compute information contentcomputeIC
DatasetsDataSet DGN_EXTID2PATHID DGN_PATHID2EXTID DGN_PATHID2NAME DO2ALLEG DO2EG DOIC DOLite2EG DOLiteTerm dotbl EG2ALLDO EG2DO EG2DOLite geneList hpotbl mpotbl NCG_EXTID2PATHID NCG_PATHID2EXTID NCG_PATHID2NAME VDGN_EXTID2PATHID VDGN_PATHID2EXTID VDGN_PATHID2NAME
doSimdoseSim
doSimdoSim
Enrichment analysis based on the DisGeNET (<http://www.disgenet.org/>)enrichDGN
enrichDGNenrichDGNv
DO Enrichment AnalysisenrichDO
enrich.internalenricher_internal
Enrichment analysis based on the DisGeNET (<http://www.disgenet.org/>)enrichHPO
Enrichment analysis based on the DisGeNET (<http://www.disgenet.org/>)enrichMPO
enrichNCGenrichNCG
Class "enrichResult" This class represents the result of enrichment analysis.enrichResult-class show,enrichResult-method summary,enrichResult-method
EXTID2NAMEEXTID2NAME
convert Gene ID to DO Termsgene2DO
geneID genericgeneID
geneInCategory genericgeneInCategory
geneSimgeneSim
GSEA_internalGSEA_internal
Class "gseaResult" This class represents the result of GSEA analysisgseahResult-class gseaResult-class show,gseaResult-method summary,gseaResult-method
DisGeNET Gene Set Enrichment AnalysisgseDGN
DO Gene Set Enrichment AnalysisgseDO
MPO Gene Set Enrichment AnalysisgseHPO
MPO Gene Set Enrichment AnalysisgseMPO
NCG Gene Set Enrichment AnalysisgseNCG
gsfiltergsfilter
doSimhpoSim
mclusterSimmclusterSim
doSimmpoSim
parse_ratioparse_ratio
rebuiding annotation datarebuildAnnoData
setReadablesetReadable
show methodshow
simplotsimplot
summary methodsummary
theme_dosetheme_dose