Package: CODEX 1.39.0

Yuchao Jiang

CODEX: A Normalization and Copy Number Variation Detection Method for Whole Exome Sequencing

A normalization and copy number variation calling procedure for whole exome DNA sequencing data. CODEX relies on the availability of multiple samples processed using the same sequencing pipeline for normalization, and does not require matched controls. The normalization model in CODEX includes terms that specifically remove biases due to GC content, exon length and targeting and amplification efficiency, and latent systemic artifacts. CODEX also includes a Poisson likelihood-based recursive segmentation procedure that explicitly models the count-based exome sequencing data.

Authors:Yuchao Jiang, Nancy R. Zhang

CODEX_1.39.0.tar.gz
CODEX_1.39.0.zip(r-4.5)CODEX_1.39.0.zip(r-4.4)CODEX_1.39.0.zip(r-4.3)
CODEX_1.39.0.tgz(r-4.5-any)CODEX_1.39.0.tgz(r-4.4-any)CODEX_1.39.0.tgz(r-4.3-any)
CODEX_1.39.0.tar.gz(r-4.5-noble)CODEX_1.39.0.tar.gz(r-4.4-noble)
CODEX_1.39.0.tgz(r-4.4-emscripten)CODEX_1.39.0.tgz(r-4.3-emscripten)
CODEX.pdf |CODEX.html
CODEX/json (API)
NEWS

# Install 'CODEX' in R:
install.packages('CODEX', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))
Datasets:

On BioConductor:CODEX-1.39.0(bioc 3.21)CODEX-1.38.0(bioc 3.20)

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

immunooncologyexomeseqnormalizationqualitycontrolcopynumbervariation

5.30 score 1 packages 33 scripts 306 downloads 72 mentions 9 exports 51 dependencies

Last updated 5 months agofrom:a803161f17. Checks:1 OK, 8 NOTE. Indexed: yes.

TargetResultLatest binary
Doc / VignettesOKMar 29 2025
R-4.5-winNOTEMar 29 2025
R-4.5-macNOTEMar 29 2025
R-4.5-linuxNOTEMar 29 2025
R-4.4-winNOTEMar 29 2025
R-4.4-macNOTEMar 29 2025
R-4.4-linuxNOTEMar 29 2025
R-4.3-winNOTEMar 29 2025
R-4.3-macNOTEMar 29 2025

Exports:choiceofKgetbambedgetcoveragegetgcgetmappnormalizenormalize2qcsegment

Dependencies:abindaskpassBHBiobaseBiocGenericsBiocIOBiocParallelBiostringsbitopsBSgenomeBSgenome.Hsapiens.UCSC.hg19codetoolscpp11crayoncurlDelayedArrayformatRfutile.loggerfutile.optionsgenericsGenomeInfoDbGenomeInfoDbDataGenomicAlignmentsGenomicRangeshttrIRangesjsonlitelambda.rlatticeMatrixMatrixGenericsmatrixStatsmimeopensslR6RCurlrestfulrRhtslibrjsonRsamtoolsrtracklayerS4ArraysS4VectorssnowSparseArraySummarizedExperimentsysUCSC.utilsXMLXVectoryaml

Using CODEX

Rendered fromCODEX_vignettes.Rnwusingutils::Sweaveon Mar 29 2025.

Last update: 2018-08-30
Started: 2014-12-13