Package: CODEX 1.39.0

Yuchao Jiang

CODEX: A Normalization and Copy Number Variation Detection Method for Whole Exome Sequencing

A normalization and copy number variation calling procedure for whole exome DNA sequencing data. CODEX relies on the availability of multiple samples processed using the same sequencing pipeline for normalization, and does not require matched controls. The normalization model in CODEX includes terms that specifically remove biases due to GC content, exon length and targeting and amplification efficiency, and latent systemic artifacts. CODEX also includes a Poisson likelihood-based recursive segmentation procedure that explicitly models the count-based exome sequencing data.

Authors:Yuchao Jiang, Nancy R. Zhang

CODEX_1.39.0.tar.gz
CODEX_1.39.0.zip(r-4.5)CODEX_1.39.0.zip(r-4.4)CODEX_1.39.0.zip(r-4.3)
CODEX_1.39.0.tgz(r-4.4-any)CODEX_1.39.0.tgz(r-4.3-any)
CODEX_1.39.0.tar.gz(r-4.5-noble)CODEX_1.39.0.tar.gz(r-4.4-noble)
CODEX_1.39.0.tgz(r-4.4-emscripten)CODEX_1.39.0.tgz(r-4.3-emscripten)
CODEX.pdf |CODEX.html
CODEX/json (API)
NEWS

# Install 'CODEX' in R:
install.packages('CODEX', repos = c('https://bioc.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Datasets:

On BioConductor:CODEX-1.39.0(bioc 3.21)CODEX-1.38.0(bioc 3.20)

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

immunooncologyexomeseqnormalizationqualitycontrolcopynumbervariation

5.33 score 1 packages 36 scripts 250 downloads 72 mentions 9 exports 52 dependencies

Last updated 2 months agofrom:a803161f17. Checks:OK: 1 NOTE: 6. Indexed: yes.

TargetResultDate
Doc / VignettesOKNov 29 2024
R-4.5-winNOTENov 29 2024
R-4.5-linuxNOTENov 29 2024
R-4.4-winNOTENov 29 2024
R-4.4-macNOTENov 29 2024
R-4.3-winNOTENov 29 2024
R-4.3-macNOTENov 29 2024

Exports:choiceofKgetbambedgetcoveragegetgcgetmappnormalizenormalize2qcsegment

Dependencies:abindaskpassBHBiobaseBiocGenericsBiocIOBiocParallelBiostringsbitopsBSgenomeBSgenome.Hsapiens.UCSC.hg19codetoolscpp11crayoncurlDelayedArrayformatRfutile.loggerfutile.optionsgenericsGenomeInfoDbGenomeInfoDbDataGenomicAlignmentsGenomicRangeshttrIRangesjsonlitelambda.rlatticeMatrixMatrixGenericsmatrixStatsmimeopensslR6RCurlrestfulrRhtslibrjsonRsamtoolsrtracklayerS4ArraysS4VectorssnowSparseArraySummarizedExperimentsysUCSC.utilsXMLXVectoryamlzlibbioc

Using CODEX

Rendered fromCODEX_vignettes.Rnwusingutils::Sweaveon Nov 29 2024.

Last update: 2018-08-30
Started: 2014-12-13