Package: AlphaBeta 1.27.0

Experimental systems | DNA methylation sampling strategies | Pedigree files of MA lineages | Pedigree files of Trees | Methylome files | Cytosine-level calls | Region-level calls | Tips for converting files from alternative callers and/or technologies | Building MA-lines Pedigree | Building Tree Pedigree | Plotting pedigrees | Pedigree of MA-lines | Tree pedigrees | Plotting divergence time (delta.t) versus methylome divergence (D.value) | Run Models | Run Model with no selection (ABneutral) | Run model with selection against spontaneous gain of methylation (ABselectMM) | Run model with selection against spontaneous loss of methylation (ABselectUU) | Run model that considers no accumulation of epimutations (ABnull) | Comparison of different models and selection of best model | Testing ABneutral vs. ABnull | Testing ABselectMM vs.ABneutral | Testing ABselectUU vs.ABneutral | Bootstrap analysis with the best fitting model(BOOTmodel) | Run Model with no selection (ABneutralSOMA) | Run model with selection against spontaneous gain of methylation (ABselectMMSOMA) | Run model with selection against spontaneous loss of methylation (ABselectUUSOMA) | Bootstrap analysis with the best fitting model (BOOTmodel)