Package: xCell2 Type: Package Title: A Tool for Generic Cell Type Enrichment Analysis Version: 1.5.0 Authors@R: c(person(given = "Almog", family = "Angel", role = c("aut", "cre"), email = "almog.angel@campus.technion.ac.il", comment = c(ORCID = "0009-0001-3297-6935")), person(given = "Dvir", family = "Aran", role = "aut", email = "dviraran@technion.ac.il", comment = c(ORCID = "0000-0001-6334-5039"))) Description: xCell2 provides methods for cell type enrichment analysis using cell type signatures. It includes three main functions - 1. xCell2Train for training custom references objects from bulk or single-cell RNA-seq datasets. 2. xCell2Analysis for conducting the cell type enrichment analysis using the custom reference. 3. xCell2GetLineage for identifying dependencies between different cell types using ontology. License: GPL (>= 3) Encoding: UTF-8 LazyData: false Depends: R (>= 4.0.0) biocViews: GeneExpression, Transcriptomics, Microarray, RNASeq, SingleCell, DifferentialExpression, ImmunoOncology, GeneSetEnrichment Imports: SummarizedExperiment, SingleCellExperiment, Rfast, singscore, AnnotationHub, ontologyIndex, tibble, dplyr, BiocParallel, Matrix, minpack.lm, pracma, methods, readr, magrittr, progress, quadprog Suggests: testthat, knitr, rmarkdown, ggplot2, randomForest, tidyr, EnhancedVolcano, BiocStyle RoxygenNote: 7.3.2 VignetteBuilder: knitr URL: https://github.com/AlmogAngel/xCell2 BugReports: https://github.com/AlmogAngel/xCell2/issues Config/pak/sysreqs: cmake make libicu-dev libpng-dev libuv1-dev libxml2-dev libssl-dev libx11-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 13:04:15 UTC RemoteUrl: https://github.com/bioc/xCell2 RemoteRef: HEAD RemoteSha: 6cf1ed07d5ff02c9116ed20a0672485897ee4bb5 NeedsCompilation: no Packaged: 2026-07-06 07:12:16 UTC; root Author: Almog Angel [aut, cre] (ORCID: ), Dvir Aran [aut] (ORCID: ) Maintainer: Almog Angel