Package: tpSVG Title: Thin plate models to detect spatially variable genes Version: 1.9.0 Authors@R: c( person("Boyi", "Guo", email = "boyi.guo.work@gmail.com", role = c("aut", "cre"), comment = c(ORCID = "0000-0003-2950-2349")), person("Lukas M.", "Weber", email = "lukas.weber.edu@gmail.com", role = c("ctb"), comment = c(ORCID = "0000-0002-3282-1730")), person("Stephanie C.", "Hicks", email = "shicks19@jhu.edu", role = c("aut"), comment = c(ORCID = "0000-0002-7858-0231"))) Description: The goal of `tpSVG` is to detect and visualize spatial variation in the gene expression for spatially resolved transcriptomics data analysis. Specifically, `tpSVG` introduces a family of count-based models, with generalizable parametric assumptions such as Poisson distribution or negative binomial distribution. In addition, comparing to currently available count-based model for spatially resolved data analysis, the `tpSVG` models improves computational time, and hence greatly improves the applicability of count-based models in SRT data analysis. License: MIT + file LICENSE URL: https://github.com/boyiguo1/tpSVG BugReports: https://github.com/boyiguo1/tpSVG/issues biocViews: Spatial, Transcriptomics, GeneExpression, Software, StatisticalMethod, DimensionReduction, Regression, Preprocessing Encoding: UTF-8 Depends: mgcv, R (>= 4.4) Roxygen: list(markdown = TRUE) RoxygenNote: 7.2.3 Imports: stats, BiocParallel, MatrixGenerics, methods, SingleCellExperiment, SummarizedExperiment, SpatialExperiment Suggests: BiocStyle, knitr, nnSVG, rmarkdown, scran, scuttle, STexampleData, escheR, ggpubr, colorspace, BumpyMatrix, sessioninfo, testthat (>= 3.0.0) VignetteBuilder: knitr Config/testthat/edition: 3 Config/pak/sysreqs: libmagick++-dev gsfonts libicu-dev libssl-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 13:02:29 UTC RemoteUrl: https://github.com/bioc/tpSVG RemoteRef: HEAD RemoteSha: 7145726ee2fcd03d756fa9d82943458bfbba22bf NeedsCompilation: no Packaged: 2026-07-03 21:57:13 UTC; root Author: Boyi Guo [aut, cre] (ORCID: ), Lukas M. Weber [ctb] (ORCID: ), Stephanie C. Hicks [aut] (ORCID: ) Maintainer: Boyi Guo