Package: toppgene Title: Gene List Enrichment Analysis using the ToppGene Suite Version: 1.1.1 Authors@R: c( person("Pariksheet Nanda", email = "pan79@pitt.edu", role = c("aut", "cre"), comment = c(ORCID = "0000-0001-9726-4552")), person("Jason Shoemaker", email = "jason.shoemaker@pitt.edu", role = "fnd", comment = c(ORCID = "0000-0003-3315-7103"))) Description: The ToppGene Suite is a one-stop portal for gene list enrichment analysis and candidate gene prioritization based on functional annotations and protein interactions network. Although the ToppCluster web application provides convenient graphical access to the ToppGene Suite, the OpenAPI 3.0 compliant interface of ToppGene is better suited for automation and reproducibility. This package includes Bioconductor class interfaces and biological examples. BiocType: Software biocViews: Clustering, GeneExpression, GeneSetEnrichment, Genetics, MotifDiscovery, Network, NetworkEnrichment, Pathways, Pharmacogenetics, Proteomics, Software, ThirdPartyClient URL: https://github.com/ImmuSystems-lab/toppgene BugReports: https://github.com/ImmuSystems-lab/toppgene/issues Depends: R (>= 4.5.0) Encoding: UTF-8 License: GPL (>= 3) Imports: BiocFileCache, httr2, IRanges, jsonlite, methods, purrr, readr, S4Vectors, xml2, yaml Suggests: BiocStyle, DFplyr (>= 1.5.0), knitr, rmarkdown, testthat (>= 3.0.0) RoxygenNote: 7.3.3 VignetteBuilder: knitr Config/testthat/edition: 3 Config/testthat/parallel: true Config/pak/sysreqs: libicu-dev libxml2-dev libssl-dev libx11-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-30 15:44:30 UTC RemoteUrl: https://github.com/bioc/toppgene RemoteRef: HEAD RemoteSha: 1c21c29c822006ba36b30023804ae983ccc5fa45 NeedsCompilation: no Packaged: 2026-07-04 13:56:38 UTC; root Author: Pariksheet Nanda [aut, cre] (ORCID: ), Jason Shoemaker [fnd] (ORCID: ) Maintainer: Pariksheet Nanda