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# CITATION file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "synapsis" in publications use:'
type: software
license: MIT
title: 'synapsis: An R package to automate the analysis of double-strand break repair
  during meiosis'
version: 1.11.0
abstract: Synapsis is a Bioconductor software package for automated (unbiased and
  reproducible) analysis of meiotic immunofluorescence datasets. The primary functions
  of the software can i) identify cells in meiotic prophase that are labelled by a
  synaptonemal complex axis or central element protein, ii) isolate individual synaptonemal
  complexes and measure their physical length, iii) quantify foci and co-localise
  them with synaptonemal complexes, iv) measure interference between synaptonemal
  complex-associated foci. The software has applications that extend to multiple species
  and to the analysis of other proteins that label meiotic prophase chromosomes. The
  software converts meiotic immunofluorescence images into R data frames that are
  compatible with machine learning methods. Given a set of microscopy images of meiotic
  spread slides, synapsis crops images around individual single cells, counts colocalising
  foci on strands on a per cell basis, and measures the distance between foci on any
  given strand.
authors:
- family-names: McNeill
  given-names: Lucy
  email: luc.mcneill@gmail.com
  orcid: https://orcid.org/0000-0003-1752-4882
repository: https://bioc.r-universe.dev
contact:
- family-names: McNeill
  given-names: Lucy
  email: luc.mcneill@gmail.com
  orcid: https://orcid.org/0000-0003-1752-4882